PDB entry 3mrh
View 3mrh on RCSB PDB site
Description: Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide N3S variant
Class: immune system
Keywords: MHC class I, HLA, IMMUNE SYSTEM, IMMUNE RESPONSE, NONAPEPTIDE, VIRAL PEPTIDE, HEPATITIS C VIRUS, NS3 PROTEIN
Deposited on
2010-04-29, released
2011-05-25
The last revision prior to the SCOPe 2.02 freeze date was dated
2011-05-25, with a file datestamp of
2011-05-20.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.217
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: HLA class I histocompatibility antigen, A-2 alpha chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA, HLA-A, HLAA
Database cross-references and differences (RAF-indexed):
- Uniprot P01892 (0-End)
- engineered mutation (244)
- Chain 'B':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Gene: B2M, Beta-2 microglubulin, CDABP0092, HDCMA22P
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d3mrhb_ - Chain 'P':
Compound: 9-meric peptide from Serine protease/NTPase/helicase NS3
Species: Hepatitis C virus genotype 1b (isolate HC-J1), synthetic [TaxId:421877]
Database cross-references and differences (RAF-indexed):
- Heterogens: HOH