PDB entry 3mq4

View 3mq4 on RCSB PDB site
Description: Metabotropic glutamate receptor mGluR7 complexed with LY341495 antagonist
Class: signaling protein
Keywords: glutamate receptors, mglur7, dimerization, glutamic acid binding, structural genomics, structural genomics consortium, sgc, signaling protein
Deposited on 2010-04-27, released 2010-06-09
The last revision prior to the SCOPe 2.04 freeze date was dated 2010-06-09, with a file datestamp of 2010-06-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.264
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Metabotropic glutamate receptor 7
    Species: Homo sapiens [TaxId:9606]
    Gene: GPRC1G, GRM7, MGLUR7
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14831
      • engineered (216)
    Domains in SCOPe 2.04: d3mq4a_
  • Heterogens: MG, Z99

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3mq4A (A:)
gamdmyaphsiriegdvtlgglfpvhakgpsgvpcgdikrengihrleamlyaldqinsd
pnllpnvtlgarildtcsrdtyaleqsltfvqaliqkdtsdvrctngeppvfvkpekvvg
vigasgssvsimvanilrlfqipqisyastapelsddrrydffsrvvppdsfqaqamvdi
vkalgwnyvstlasegsygekgvesftqiskeagglsiaqsvripqerkdrtidfdriik
qlldtpnsravvifandedikqilaaakradqvghflwvgsdswgskinplhqhediaeg
aitiqpkratvegfdayftsrtlennrrnvwfaeyweenfnckltisgskkedtdrkctg
qerigkdsnyeqegkvqfvidavyamahalhhmnkdlcadyrgvcpemeqaggkkllkyi
rnvnfngsagtpvmfnkngdapgrydifqyqttntsnpgyrligqwtdelqlniedmqwg
k

    Sequence, based on observed residues (ATOM records): (download) 
    >3mq4A (A:)
hsiriegdvtlgglfpvhakgcgdikrengihrleamlyaldqinsdpnllpnvtlgari
ldtcsrdtyaleqsltfvqaliqkdtkpekvvgvigasgssvsimvanilrlfqipqisy
astapelsddrrydffsrvvppdsfqaqamvdivkalgwnyvstlgsygekgvesftqis
gglsiaqsvripqedfdriikqlldtavvifandedikqilhflwvgsegaitiqpkrat
vegfdayftsrtlennrrnvwfaeyweenfncklkctgqerigkdsnyeqegkvqfvida
vyamahalhhmnkdlcavcpemeqaggkkllkyirnvnfngsagtpvmfnkngdapgryd
ifqyqnpgyrligqwtdelqlniedm