PDB entry 3mnn

View 3mnn on RCSB PDB site
Description: A Ruthenium Antitumour Agent Forms Specific Histone Protein Adducts in the Nucleosome Core
Class: structural protein/DNA
Keywords: NUCLEOSOME, NCP, RUTHENIUM, RAPTA-C, STRUCTURAL PROTEIN-DNA complex
Deposited on 2010-04-22, released 2011-04-06
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-04-06, with a file datestamp of 2011-04-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.248
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone H3.2
    Species: Xenopus laevis [TaxId:8355]
    Gene: HISTONE H3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P84233
      • see remark 999 (101)
    Domains in SCOPe 2.02: d3mnna_
  • Chain 'B':
    Compound: histone h4
    Species: Xenopus laevis [TaxId:8355]
    Gene: HISTONE H4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3mnnb_
  • Chain 'C':
    Compound: histone h2a
    Species: Xenopus laevis [TaxId:8355]
    Gene: HISTONE H2A, LOC494591
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3mnnc_
  • Chain 'D':
    Compound: Histone H2B 1.1
    Species: Xenopus laevis [TaxId:8355]
    Gene: HISTONE H2B
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02281 (Start-124)
      • see remark 999 (31)
    Domains in SCOPe 2.02: d3mnnd_
  • Chain 'E':
    Compound: Histone H3.2
    Species: Xenopus laevis [TaxId:8355]
    Gene: HISTONE H3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P84233
      • see remark 999 (101)
    Domains in SCOPe 2.02: d3mnne_
  • Chain 'F':
    Compound: histone h4
    Species: Xenopus laevis [TaxId:8355]
    Gene: HISTONE H4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3mnnf_
  • Chain 'G':
    Compound: histone h2a
    Species: Xenopus laevis [TaxId:8355]
    Gene: HISTONE H2A, LOC494591
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3mnng_
  • Chain 'H':
    Compound: Histone H2B 1.1
    Species: Xenopus laevis [TaxId:8355]
    Gene: HISTONE H2B
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02281 (Start-124)
      • see remark 999 (31)
    Domains in SCOPe 2.02: d3mnnh_
  • Chain 'I':
    Compound: DNA (145-mer)
    Species: synthetic, synthetic
  • Chain 'J':
    Compound: DNA (145-mer)
    Species: synthetic, synthetic
  • Heterogens: SO4, MG, RU, MML, PTW, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3mnnA (A:)
artkqtarkstggkaprkqlatkaarksapatggvkkphryrpgtvalreirryqkstel
lirklpfqrlvreiaqdfktdlrfqssavmalqeaseaylvalfedtnlcaihakrvtim
pkdiqlarrirgera

    Sequence, based on observed residues (ATOM records): (download) 
    >3mnnA (A:)
phryrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlrfqssavmalqease
aylvalfedtnlcaihakrvtimpkdiqlarrirger

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3mnnB (B:)
sgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlkv
flenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg

    Sequence, based on observed residues (ATOM records): (download) 
    >3mnnB (B:)
vlrdniqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrkt
vtamdvvyalkrqgrtlygfgg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3mnnC (C:)
sgrgkqggktrakaktrssraglqfpvgrvhrllrkgnyaervgagapvylaavleylta
eilelagnaardnkktriiprhlqlavrndeelnkllgrvtiaqggvlpniqsvllpkk

    Sequence, based on observed residues (ATOM records): (download) 
    >3mnnC (C:)
aktrssraglqfpvgrvhrllrkgnyaervgagapvylaavleyltaeilelagnaardn
kktriiprhlqlavrndeelnkllgrvtiaqggvlpniqsvllpkk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3mnnD (D:)
pepaksapapkkgskkavtktqkkdgkkrrktrkesyaiyvykvlkqvhpdtgisskams
imnsfvndvferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtk
ytsak

    Sequence, based on observed residues (ATOM records): (download) 
    >3mnnD (D:)
ktrkesyaiyvykvlkqvhpdtgisskamsimnsfvndvferiageasrlahynkrstit
sreiqtavrlllpgelakhavsegtkavtkytsak

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3mnnE (E:)
artkqtarkstggkaprkqlatkaarksapatggvkkphryrpgtvalreirryqkstel
lirklpfqrlvreiaqdfktdlrfqssavmalqeaseaylvalfedtnlcaihakrvtim
pkdiqlarrirgera

    Sequence, based on observed residues (ATOM records): (download) 
    >3mnnE (E:)
phryrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlrfqssavmalqease
aylvalfedtnlcaihakrvtimpkdiqlarrirger

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3mnnF (F:)
sgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlkv
flenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg

    Sequence, based on observed residues (ATOM records): (download) 
    >3mnnF (F:)
krhrkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtyteh
akrktvtamdvvyalkrqgrtlygfgg

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >3mnnG (G:)
sgrgkqggktrakaktrssraglqfpvgrvhrllrkgnyaervgagapvylaavleylta
eilelagnaardnkktriiprhlqlavrndeelnkllgrvtiaqggvlpniqsvllpkk

    Sequence, based on observed residues (ATOM records): (download) 
    >3mnnG (G:)
aktrssraglqfpvgrvhrllrkgnyaervgagapvylaavleyltaeilelagnaardn
kktriiprhlqlavrndeelnkllgrvtiaqggvlpniqsvllpkk

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3mnnH (H:)
pepaksapapkkgskkavtktqkkdgkkrrktrkesyaiyvykvlkqvhpdtgisskams
imnsfvndvferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtk
ytsak

    Sequence, based on observed residues (ATOM records): (download) 
    >3mnnH (H:)
ktrkesyaiyvykvlkqvhpdtgisskamsimnsfvndvferiageasrlahynkrstit
sreiqtavrlllpgelakhavsegtkavtkytsak

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.