PDB entry 3mly

View 3mly on RCSB PDB site
Description: Crystal structure of anti-HIV-1 V3 Fab 3074 in complex with a UR29 V3 peptide
Class: immune system
Keywords: human monoclonal antibody, Fab, HIV-1, gp120, third variable loop, antibody-antigen interaction, IMMUNE SYSTEM
Deposited on 2010-04-18, released 2010-07-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-17, with a file datestamp of 2019-07-12.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3MLY (0-229)
    Domains in SCOPe 2.08: d3mlyh1, d3mlyh2
  • Chain 'I':
    Compound: Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3MLY (0-229)
    Domains in SCOPe 2.08: d3mlyi1, d3mlyi2
  • Chain 'L':
    Compound: Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3MLY (0-213)
    Domains in SCOPe 2.08: d3mlyl1, d3mlyl2
  • Chain 'M':
    Compound: Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3MLY (0-213)
    Domains in SCOPe 2.08: d3mlym1, d3mlym2
  • Chain 'P':
    Compound: HIV-1 gp120 third variable region (V3) crown
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • PDB 3MLY
  • Chain 'Q':
    Compound: HIV-1 gp120 third variable region (V3) crown
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • PDB 3MLY
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3mlyH (H:)
    qvqlqesgpglvkpsetlsltctvsggsisgfhwswirqppgkgleyigyiyysgstsyn
    pslksrvsmsvdtsrnqfslelssvtaadtavyycardfgeyhydgrgfqcegfdlwgqg
    tlvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtf
    pavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc
    

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3mlyI (I:)
    qvqlqesgpglvkpsetlsltctvsggsisgfhwswirqppgkgleyigyiyysgstsyn
    pslksrvsmsvdtsrnqfslelssvtaadtavyycardfgeyhydgrgfqcegfdlwgqg
    tlvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtf
    pavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc
    

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3mlyL (L:)
    qsvltqppsvsaapgqkvtiscsgsssnignnmvswyqqhpgtapklliyenskrpsgip
    drfsgsrsgtsatlgiiglqtgdeaeyycatwdgslrtvfgggtkltvlsqpkaapsvtl
    fppsseelqankatlvclisdfypgavtvawkadsspvragvetttpskqsnnkyaassy
    lsltpeqwkshrsyscqvthegstvektvaptec
    

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3mlyM (M:)
    qsvltqppsvsaapgqkvtiscsgsssnignnmvswyqqhpgtapklliyenskrpsgip
    drfsgsrsgtsatlgiiglqtgdeaeyycatwdgslrtvfgggtkltvlsqpkaapsvtl
    fppsseelqankatlvclisdfypgavtvawkadsspvragvetttpskqsnnkyaassy
    lsltpeqwkshrsyscqvthegstvektvaptec
    

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.