PDB entry 3mkn

View 3mkn on RCSB PDB site
Description: Crystal structure of the E. coli pyrimidine nucleosidase YeiK bound to a competitive inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: Pyrimidine nucleoside hydrolase, nucleotide metabolism, enzyme-inhibitor complex, metalloenzyme, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2010-04-15, released 2010-12-01
The last revision prior to the SCOPe 2.05 freeze date was dated 2010-12-22, with a file datestamp of 2010-12-17.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.175
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Putative uncharacterized protein YeiK
    Species: Escherichia coli [TaxId:83333]
    Gene: YEIK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3mkna_
  • Chain 'B':
    Compound: Putative uncharacterized protein YeiK
    Species: Escherichia coli [TaxId:83333]
    Gene: YEIK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3mknb_
  • Chain 'C':
    Compound: Putative uncharacterized protein YeiK
    Species: Escherichia coli [TaxId:83333]
    Gene: YEIK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3mknc_
  • Chain 'D':
    Compound: Putative uncharacterized protein YeiK
    Species: Escherichia coli [TaxId:83333]
    Gene: YEIK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3mknd_
  • Heterogens: CA, DNB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3mknA (A:)
gshmekrkiildcdpghddaiaimmaakhpaidllgitivagnqtldktlinglnvcqkl
einvpvyagmpqpimrqqivadnihgdtgldgpvfepltrqaesthavkyiidtlmasdg
ditlvpvgplsniavamrmqpailpkireivlmggaygtgnftpsaefnifadpeaarvv
ftsgvplvmmgldltnqtvctpdviarmeraggpagelfsdimnftlktqfenyglaggp
vhdatcigylinpdgiktqemyvevdvnsgpcygrtvcdelgvlgkpantkvgitidtdw
fwglveecvrgyikth

    Sequence, based on observed residues (ATOM records): (download) 
    >3mknA (A:)
krkiildcdpghddaiaimmaakhpaidllgitivagnqtldktlinglnvcqkleinvp
vyagmpqpimrqqivadnihgdtgldgpvfepltrqaesthavkyiidtlmasdgditlv
pvgplsniavamrmqpailpkireivlmggaygtgnftpsaefnifadpeaarvvftsgv
plvmmgldltnqtvctpdviarmeraggpagelfsdimnftlktqfepvhdatcigylin
pdgiktqemyvevdvnsgpcygrtvcdelgvlgkpantkvgitidtdwfwglveecvrgy
ikt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3mknB (B:)
gshmekrkiildcdpghddaiaimmaakhpaidllgitivagnqtldktlinglnvcqkl
einvpvyagmpqpimrqqivadnihgdtgldgpvfepltrqaesthavkyiidtlmasdg
ditlvpvgplsniavamrmqpailpkireivlmggaygtgnftpsaefnifadpeaarvv
ftsgvplvmmgldltnqtvctpdviarmeraggpagelfsdimnftlktqfenyglaggp
vhdatcigylinpdgiktqemyvevdvnsgpcygrtvcdelgvlgkpantkvgitidtdw
fwglveecvrgyikth

    Sequence, based on observed residues (ATOM records): (download) 
    >3mknB (B:)
krkiildcdpghddaiaimmaakhpaidllgitivagnqtldktlinglnvcqkleinvp
vyagmpqpimrqqivagldgpvfepltrqaesthavkyiidtlmasdgditlvpvgplsn
iavamrmqpailpkireivlmggaygtgnftpsaefnifadpeaarvvftsgvplvmmgl
dltnqtvctpdviarmeraggpagelfsdimnftlktqfenyglaggpvhdatcigylin
pdgiktqemyvevdvnsgpcygrtvcdelgvlgkpantkvgitidtdwfwglveecvrgy
i

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3mknC (C:)
gshmekrkiildcdpghddaiaimmaakhpaidllgitivagnqtldktlinglnvcqkl
einvpvyagmpqpimrqqivadnihgdtgldgpvfepltrqaesthavkyiidtlmasdg
ditlvpvgplsniavamrmqpailpkireivlmggaygtgnftpsaefnifadpeaarvv
ftsgvplvmmgldltnqtvctpdviarmeraggpagelfsdimnftlktqfenyglaggp
vhdatcigylinpdgiktqemyvevdvnsgpcygrtvcdelgvlgkpantkvgitidtdw
fwglveecvrgyikth

    Sequence, based on observed residues (ATOM records): (download) 
    >3mknC (C:)
krkiildcdpghddaiaimmaakhpaidllgitivagnqtldktlinglnvcqkleinvp
vyagmpqpimrqqivadtgldgpvfepltrqaesthavkyiidtlmasdgditlvpvgpl
sniavamrmqpailpkireivlmggaygtgnftpsaefnifadpeaarvvftsgvplvmm
gldltnqtvctpdviarmeraggpagelfsdimnftgpvhdatcigylinpdgiktqemy
vevdvnsgpcygrtvcdelgvlgkpantkvgitidtdwfwglveecvrgyik

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3mknD (D:)
gshmekrkiildcdpghddaiaimmaakhpaidllgitivagnqtldktlinglnvcqkl
einvpvyagmpqpimrqqivadnihgdtgldgpvfepltrqaesthavkyiidtlmasdg
ditlvpvgplsniavamrmqpailpkireivlmggaygtgnftpsaefnifadpeaarvv
ftsgvplvmmgldltnqtvctpdviarmeraggpagelfsdimnftlktqfenyglaggp
vhdatcigylinpdgiktqemyvevdvnsgpcygrtvcdelgvlgkpantkvgitidtdw
fwglveecvrgyikth

    Sequence, based on observed residues (ATOM records): (download) 
    >3mknD (D:)
krkiildcdpghddaiaimmaakhpaidllgitivagnqtldktlinglnvcqkleinvp
vyagmpqpimrqqivadnihgdtgldgpvfepltrqaesthavkyiidtlmasdgditlv
pvgplsniavamrmqpailpkireivlmggaygtgnftpsaefnifadpeaarvvftsgv
plvmmgldltnqtvctpdviarmeraggpagelfsdimnftlktqfegpvhdatcigyli
npdgiktqemyvevdvnsgpcygrtvcdelgvlgkpantkvgitidtdwfwglveecvrg
yik