PDB entry 3mj5

View 3mj5 on RCSB PDB site
Description: Severe Acute Respiratory Syndrome-Coronavirus Papain-Like Protease Inhibitors: Design, Synthesis, Protein-Ligand X-ray Structure and Biological Evaluation
Deposited on 2010-04-12, released 2010-06-30
The last revision was dated 2010-07-14, with a file datestamp of 2010-07-09.
Experiment type: XRAY
Resolution: 2.63 Å
R-factor: 0.211
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Replicase polyprotein 1a
    Species: SARS coronavirus [TaxId:227859]
    Gene: 1a, ORF1 (nsp3) residues 1544-1855
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Replicase polyprotein 1a
    Species: SARS coronavirus [TaxId:227859]
    Gene: 1a, ORF1 (nsp3) residues 1544-1855
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GRM, ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.07, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3mj5A (A:)
    mevktikvfttvdntnlhtqlvdmsmtygqqfgptyldgadvtkikphvnhegktffvlp
    sddtlrseafeyyhtldesflgrymsalnhtkkwkfpqvggltsikwadnncylssvlla
    lqqlevkfnapalqeayyraragdaanfcalilaysnktvgelgdvretmthllqhanle
    sakrvlnvvckhcgqktttltgveavmymgtlsydnlktgvsipcvcgrdatqylvqqes
    sfvmmsappaeyklqqgtflcaneytgnyqcghythitaketlyridgahltkmseykgp
    vtdvfyketsytttik
    

    Sequence, based on observed residues (ATOM records):
    >3mj5A (A:)
    ktikvfttvdntnlhtqlvdmsmtygqqfgptyldgadvtkikphvnhegktffvlpsdd
    tlrseafeyyhtldesflgrymsalnhtkkwkfpqvggltsikwadnncylssvllalqq
    levkfnapalqeayyraragdaanfcalilaysnktvgelgdvretmthllqhanlesak
    rvlnvvckhcgqktttltgveavmymgtlsydnlktgvsipcvcgrdatqylvqqessfv
    mmsappaeyklqqgtflcaneytgnyqcghythitaketlyridgahltkmseykgpvtd
    vfyketsyttti
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3mj5B (B:)
    mevktikvfttvdntnlhtqlvdmsmtygqqfgptyldgadvtkikphvnhegktffvlp
    sddtlrseafeyyhtldesflgrymsalnhtkkwkfpqvggltsikwadnncylssvlla
    lqqlevkfnapalqeayyraragdaanfcalilaysnktvgelgdvretmthllqhanle
    sakrvlnvvckhcgqktttltgveavmymgtlsydnlktgvsipcvcgrdatqylvqqes
    sfvmmsappaeyklqqgtflcaneytgnyqcghythitaketlyridgahltkmseykgp
    vtdvfyketsytttik
    

    Sequence, based on observed residues (ATOM records):
    >3mj5B (B:)
    tffvlpsddtlrseafeyyhtldesflgrymsalnhtkkwkfpqvggltsikwadnncyl
    ssvllalqqlevkfnapalqeayyraragdaanfcalilaysnktvgelgdvretmthll
    qhanlesakrvlnvvckhcgqktttltgveavmymgtlsydnlktgvsipcvcgrdatqy
    lvqqessfvmmsappaeyklqqgtflcaneytgnyqcghythitaketlyridgahltkm
    seykgpvtdvfyketsytttik