PDB entry 3mfw

View 3mfw on RCSB PDB site
Description: Crystal structure of human arginase I in complex with L-2-aminohistidine and sulphate
Class: hydrolase
Keywords: manganese coordination, 2-aminoimidazole derivative, structure based design, HYDROLASE
Deposited on 2010-04-04, released 2010-05-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2010-06-09, with a file datestamp of 2010-06-04.
Experiment type: XRAY
Resolution: 1.47 Å
R-factor: 0.149
AEROSPACI score: 0.65 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Arginase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: ARG1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3mfwa_
  • Chain 'B':
    Compound: Arginase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: ARG1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3mfwb_
  • Heterogens: SO4, B3U, MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3mfwA (A:)
msaksrtigiigapfskgqprggveegptvlrkaglleklkeqecdvkdygdlpfadipn
dspfqivknprsvgkaseqlagkvaevkkngrislvlggdhslaigsisgharvhpdlgv
iwvdahtdintpltttsgnlhgqpvsfllkelkgkipdvpgfswvtpcisakdivyiglr
dvdpgehyilktlgikyfsmtevdrlgigkvmeetlsyllgrkkrpihlsfdvdgldpsf
tpatgtpvvggltyreglyiteeiyktgllsgldimevnpslgktpeevtrtvntavait
lacfglaregnhkpidylnppk

    Sequence, based on observed residues (ATOM records): (download) 
    >3mfwA (A:)
srtigiigapfskgqprggveegptvlrkaglleklkeqecdvkdygdlpfadipndspf
qivknprsvgkaseqlagkvaevkkngrislvlggdhslaigsisgharvhpdlgviwvd
ahtdintpltttsgnlhgqpvsfllkelkgkipdvpgfswvtpcisakdivyiglrdvdp
gehyilktlgikyfsmtevdrlgigkvmeetlsyllgrkkrpihlsfdvdgldpsftpat
gtpvvggltyreglyiteeiyktgllsgldimevnpslgktpeevtrtvntavaitlacf
glaregnhkpidyln

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3mfwB (B:)
msaksrtigiigapfskgqprggveegptvlrkaglleklkeqecdvkdygdlpfadipn
dspfqivknprsvgkaseqlagkvaevkkngrislvlggdhslaigsisgharvhpdlgv
iwvdahtdintpltttsgnlhgqpvsfllkelkgkipdvpgfswvtpcisakdivyiglr
dvdpgehyilktlgikyfsmtevdrlgigkvmeetlsyllgrkkrpihlsfdvdgldpsf
tpatgtpvvggltyreglyiteeiyktgllsgldimevnpslgktpeevtrtvntavait
lacfglaregnhkpidylnppk

    Sequence, based on observed residues (ATOM records): (download) 
    >3mfwB (B:)
srtigiigapfskgqprggveegptvlrkaglleklkeqecdvkdygdlpfadipndspf
qivknprsvgkaseqlagkvaevkkngrislvlggdhslaigsisgharvhpdlgviwvd
ahtdintpltttsgnlhgqpvsfllkelkgkipdvpgfswvtpcisakdivyiglrdvdp
gehyilktlgikyfsmtevdrlgigkvmeetlsyllgrkkrpihlsfdvdgldpsftpat
gtpvvggltyreglyiteeiyktgllsgldimevnpslgktpeevtrtvntavaitlacf
glaregnhkpidyl