PDB entry 3mfs

View 3mfs on RCSB PDB site
Description: CASK-4M CaM Kinase Domain, AMPPNP
Class: transferase
Keywords: Catalytic mechanism, kinase catalysis, Mg2+-mediated phosphate transfer, protein kinase, TRANSFERASE
Deposited on 2010-04-03, released 2010-04-28
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.221
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peripheral plasma membrane protein CASK
    Species: Homo sapiens [TaxId:9606]
    Gene: CASK, LIN2
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14936
      • engineered (35)
      • engineered (158-159)
      • engineered (175)
    Domains in SCOPe 2.06: d3mfsa_
  • Heterogens: ANP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3mfsA (A:)
gspgisgggggildmadddvlfedvyelcevigkgafsvvrrcinretgqqfavkivdva
kftsspglstedlkreasichmlkhphivelletyssdgmlymvfefmdgadlcfeivkr
adagfvyseavashymrqilealrychdnniihrdvkpenvllaskensapvklgdfgva
iqlgesglvaggrvgtphfmapevvkrepygkpvdvwgcgvilfillsgclpfygtkerl
fegiikgkykmnprqwshisesakdlvrrmlmldpaeritvyealnhpwlkerdryayki
hlpetveqlrkfnarrklkgavlaavsshkfnsfygdppeelpdfsedpts

    Sequence, based on observed residues (ATOM records): (download) 
    >3mfsA (A:)
ddvlfedvyelcevigkgafsvvrrcinretgqqfavkivdvakftsspglstedlkrea
sichmlkhphivelletyssdgmlymvfefmdgadlcfeivkradagfvyseavashymr
qilealrychdnniihrdvkpenvllaskensapvklgdfgvaiqlgesglvaggrvgtp
hfmapevvkrepygkpvdvwgcgvilfillsgclpfygtkerlfegiikgkykmnprqws
hisesakdlvrrmlmldpaeritvyealnhpwlkerdryaykihlpetveqlrkfnarrk
lkg