SCOPe 2.07: Structural Classification of Proteins

PDB entry 3mdj

View 3mdj on RCSB PDB site
Description: ER Aminopeptidase, ERAP1, Bound to the Zinc Aminopeptidase Inhibitor, Bestatin
Class: Hydrolase/Hydrolase Inhibitor
Keywords: aminopeptidase, Zn binding protein, ER, Hydrolase-Hydrolase Inhibitor complex
Deposited on 2010-03-30, released 2011-03-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.95 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: endoplasmic reticulum aminopeptidase 1
Species: Homo sapiens [TaxId:9606]
Gene: ERAP1, APPILS, ARTS1, KIAA0525, UNQ584/PRO1154
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NZ08
  - see remark 999 (309)
  - see remark 999 (491)
  - see remark 999 (693)
Domains in SCOPe 2.07: d3mdja1, d3mdja2, d3mdja3, d3mdja4
Chain 'B':
Compound: endoplasmic reticulum aminopeptidase 1
Species: Homo sapiens [TaxId:9606]
Gene: ERAP1, APPILS, ARTS1, KIAA0525, UNQ584/PRO1154
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NZ08
  - see remark 999 (309)
  - see remark 999 (491)
  - see remark 999 (693)
Domains in SCOPe 2.07: d3mdjb1, d3mdjb2, d3mdjb3, d3mdjb4
Chain 'C':
Compound: endoplasmic reticulum aminopeptidase 1
Species: Homo sapiens [TaxId:9606]
Gene: ERAP1, APPILS, ARTS1, KIAA0525, UNQ584/PRO1154
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NZ08
  - see remark 999 (309)
  - see remark 999 (491)
  - see remark 999 (693)
Domains in SCOPe 2.07: d3mdjc1, d3mdjc2, d3mdjc3, d3mdjc4
Heterogens: ZN, BES, NAG, BMA, MAN

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>3mdjA (A:)
aspkrsdgtpfpwnkirlpeyvipvhydllihanlttltfwgttkveitasqptstiilh
shhlqisratlrkgagerlseeplqvlehprqeqiallapepllvglpytvvihyagnls
etfhgfykstyrtkegelrilastqfeptaarmafpcfdepafkasfsikirreprhlai
snmplvksvtvaegliedhfdvtvkmstylvafiisdfesvskitksgvkvsvyavpdki
nqadyaldaavtllefyedyfsipyplpkqdlaaipdfqsgamenwglttyresallfda
ekssassklditmtvahelahqwfgnlvtmewwndlwlnegfakfmefvsvsvthpelkv
gdyffgkcfdamevdalnsshpvstpvenpaqiremfddvsydkgacilnmlreylsada
fksgivqylqkhsykntknedlwdsmasicptdgvkgmdgfcsrsqhssssshwhqervd
vktmmntwtlqrgfplititvrgrnvhmkqehymkgsdgapdtgylwhvpltfitsksdm
vhrfllktktdvlilpeevewikfnvgmngyyivhyeddgwdsltgllkgthtavssndr
aslinnafqlvsigklsiekaldlslylkheteimpvfqglnelipmyklmekrdmneve
tqfkaflirllrdlidkqtwtdegsvsermlrsellllacvhnyqpcvqraegyfrkwke
sngnlslpvdvtlavfavgaqstegwdflyskyqfslssteksqiefalcrtqnkeklqw
lldesfkgdkiktqefpqiltligrnpvgyplawqflrknwnklvqkfelgsssiahmvm
gttnqfstrtrleevkgffsslkengsqlrcvqqtietieenigwmdknfdkirvwlqse
klehdpeadatglermlesrg

Sequence, based on observed residues (ATOM records): (download)

>3mdjA (A:)
pfpwnkirlpeyvipvhydllihanlttltfwgttkveitasqptstiilhshhlqisra
tlrkgrlseeplqvlehprqeqiallapepllvglpytvvihyagnlsetfhgfykstyr
tkegelrilastqfeptaarmafpcfdepafkasfsikirreprhlaisnmplvksvtva
egliedhfdvtvkmstylvafiisdfesvskitksgvkvsvyavpdkinqadyaldaavt
llefyedyfsipyplpkqdlaaipdfqsgamenwglttyresallfdaekssasskldit
mtvahelahqwfgnlvtmewwndlwlnegfakfmefvsvsvthpelkvgdyffgkcfdam
evdalnssddvsydkgacilnmlreylsadafksgivqylqkhsykntknedlwdsmasi
vdvktmmntwtlqrgfplititvrgrnvhmkqehymkapdtgylwhvpltfitsksdmvh
rfllktktdvlilpeevewikfnvgmngyyivhyeddgwdsltgllkgthtavssndras
linnafqlvsigklsiekaldlslylkheteimpvfqglnelipmyklmekrdmnevetq
fkaflirllrdlidkqtwtdegsvsermlrsellllacvhnyqpcvqraegyfrkwkesn
gnlslpvdvtlavfavgaqstegwdflyskyqfslssteksqiefalcrtqnkeklqwll
desfkgdkiktqefpqiltligrnpvgyplawqflrknwnklvqksssiahmvmgttnqf
strtrleevkcvqqtietieenigwmdknfdkirvwlq

Chain 'B':
Sequence, based on SEQRES records: (download)

>3mdjB (B:)
aspkrsdgtpfpwnkirlpeyvipvhydllihanlttltfwgttkveitasqptstiilh
shhlqisratlrkgagerlseeplqvlehprqeqiallapepllvglpytvvihyagnls
etfhgfykstyrtkegelrilastqfeptaarmafpcfdepafkasfsikirreprhlai
snmplvksvtvaegliedhfdvtvkmstylvafiisdfesvskitksgvkvsvyavpdki
nqadyaldaavtllefyedyfsipyplpkqdlaaipdfqsgamenwglttyresallfda
ekssassklditmtvahelahqwfgnlvtmewwndlwlnegfakfmefvsvsvthpelkv
gdyffgkcfdamevdalnsshpvstpvenpaqiremfddvsydkgacilnmlreylsada
fksgivqylqkhsykntknedlwdsmasicptdgvkgmdgfcsrsqhssssshwhqervd
vktmmntwtlqrgfplititvrgrnvhmkqehymkgsdgapdtgylwhvpltfitsksdm
vhrfllktktdvlilpeevewikfnvgmngyyivhyeddgwdsltgllkgthtavssndr
aslinnafqlvsigklsiekaldlslylkheteimpvfqglnelipmyklmekrdmneve
tqfkaflirllrdlidkqtwtdegsvsermlrsellllacvhnyqpcvqraegyfrkwke
sngnlslpvdvtlavfavgaqstegwdflyskyqfslssteksqiefalcrtqnkeklqw
lldesfkgdkiktqefpqiltligrnpvgyplawqflrknwnklvqkfelgsssiahmvm
gttnqfstrtrleevkgffsslkengsqlrcvqqtietieenigwmdknfdkirvwlqse
klehdpeadatglermlesrg

Sequence, based on observed residues (ATOM records): (download)

>3mdjB (B:)
pfpwnkirlpeyvipvhydllihanlttltfwgttkveitasqptstiilhshhlqisra
tlrkgagerlseeplqvlehprqeqiallapepllvglpytvvihyagnlsetfhgfyks
tyrtkegelrilastqfeptaarmafpcfdepafkasfsikirreprhlaisnmplvksv
tvaegliedhfdvtvkmstylvafiisdfesvskitksgvkvsvyavpdkinqadyalda
avtllefyedyfsipyplpkqdlaaipdfqsgamenwglttyresallfdaekssasskl
ditmtvahelahqwfgnlvtmewwndlwlnegfakfmefvsvsvthpelkvgdyffgkcf
damevdalnssddvsydkgacilnmlreylsadafksgivqylqkhsykntknedlwdsm
asivdvktmmntwtlqrgfplititvrgrnvhmkqehymkapdtgylwhvpltfitsksd
mvhrfllktktdvlilpeevewikfnvgmngyyivhyeddgwdsltgllkgthtavssnd
raslinnafqlvsigklsiekaldlslylkheteimpvfqglnelipmyklmekrdmnev
etqfkaflirllrdlidkqtwtdegsvsermlrsellllacvhnyqpcvqraegyfrkwk
esngnlslpvdvtlavfavgaqstegwdflyskyqfslssteksqiefalcrtqnkeklq
wlldesfkgdkiktqefpqiltligrnpvgyplawqflrknwnklvqksssiahmvmgtt
nqfstrtrleevkcvqqtietieenigwmdknfdkirvwlq

Chain 'C':
Sequence, based on SEQRES records: (download)

>3mdjC (C:)
aspkrsdgtpfpwnkirlpeyvipvhydllihanlttltfwgttkveitasqptstiilh
shhlqisratlrkgagerlseeplqvlehprqeqiallapepllvglpytvvihyagnls
etfhgfykstyrtkegelrilastqfeptaarmafpcfdepafkasfsikirreprhlai
snmplvksvtvaegliedhfdvtvkmstylvafiisdfesvskitksgvkvsvyavpdki
nqadyaldaavtllefyedyfsipyplpkqdlaaipdfqsgamenwglttyresallfda
ekssassklditmtvahelahqwfgnlvtmewwndlwlnegfakfmefvsvsvthpelkv
gdyffgkcfdamevdalnsshpvstpvenpaqiremfddvsydkgacilnmlreylsada
fksgivqylqkhsykntknedlwdsmasicptdgvkgmdgfcsrsqhssssshwhqervd
vktmmntwtlqrgfplititvrgrnvhmkqehymkgsdgapdtgylwhvpltfitsksdm
vhrfllktktdvlilpeevewikfnvgmngyyivhyeddgwdsltgllkgthtavssndr
aslinnafqlvsigklsiekaldlslylkheteimpvfqglnelipmyklmekrdmneve
tqfkaflirllrdlidkqtwtdegsvsermlrsellllacvhnyqpcvqraegyfrkwke
sngnlslpvdvtlavfavgaqstegwdflyskyqfslssteksqiefalcrtqnkeklqw
lldesfkgdkiktqefpqiltligrnpvgyplawqflrknwnklvqkfelgsssiahmvm
gttnqfstrtrleevkgffsslkengsqlrcvqqtietieenigwmdknfdkirvwlqse
klehdpeadatglermlesrg

Sequence, based on observed residues (ATOM records): (download)

>3mdjC (C:)
pfpwnkirlpeyvipvhydllihanlttltfwgttkveitasqptstiilhshhlqisra
tlrkgerlseeplqvlehprqeqiallapepllvglpytvvihyagnlsetfhgfyksty
rtkegelrilastqfeptaarmafpcfdepafkasfsikirreprhlaisnmplvksvtv
aegliedhfdvtvkmstylvafiisdfesvskitksgvkvsvyavpdkinqadyaldaav
tllefyedyfsipyplpkqdlaaipdfqsgamenwglttyresallfdaekssasskldi
tmtvahelahqwfgnlvtmewwndlwlnegfakfmefvsvsvthpelkvgdyffgkcfda
mevdalnssddvsydkgacilnmlreylsadafksgivqylqkhsykntknedlwdsmas
ivdvktmmntwtlqrgfplititvrgrnvhmkqehymkapdtgylwhvpltfitsksdmv
hrfllktktdvlilpeevewikfnvgmngyyivhyeddgwdsltgllkgthtavssndra
slinnafqlvsigklsiekaldlslylkheteimpvfqglnelipmyklmekrdmnevet
qfkaflirllrdlidkqtwtdegsvsermlrsellllacvhnyqpcvqraegyfrkwkes
ngnlslpvdvtlavfavgaqstegwdflyskyqfslssteksqiefalcrtqnkeklqwl
ldesfkgdkiktqefpqiltligrnpvgyplawqflrknwnklvqksssiahmvmgttnq
fstrtrleevkcvqqtietieenigwmdknfdkirvwlq