PDB entry 3mb8

View 3mb8 on RCSB PDB site
Description: Crystal structure of purine nucleoside phosphorylase from toxoplasma gondii in complex with immucillin-H
Class: transferase
Keywords: PNP, Purine nucleoside phosphorylase, Immucillin H, ImmH, TRANSFERASE
Deposited on 2010-03-25, released 2011-04-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: purine nucleoside phosphorylase
    Species: Toxoplasma gondii [TaxId:5811]
    Gene: PNP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2HXR2 (3-249)
      • expression tag (2)
      • see remark 999 (235)
    Domains in SCOPe 2.07: d3mb8a1, d3mb8a2
  • Chain 'B':
    Compound: purine nucleoside phosphorylase
    Species: Toxoplasma gondii [TaxId:5811]
    Gene: PNP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2HXR2 (3-249)
      • expression tag (2)
      • see remark 999 (235)
    Domains in SCOPe 2.07: d3mb8b1, d3mb8b2
  • Heterogens: IMH, PO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3mb8A (A:)
mplmqgmevqphirlrkedvepvviivgdparteevanmcekkqelaynreyrsfrvvyd
sqpitvishgigcpgtsiaieelaylgakviiragtcgslkpktlkqgdvcvtyaavnet
glisnilpegfpcvatphvyqalmdaakelgieaasgigvtqdyfyqngilpsklemysk
ccdvidmemsgvlglcqargiatcgilavdgsplqwdegdydatgvkattgkenmvkitl
kacanlrrqykgefeayveqkliseedlnsavdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3mb8A (A:)
lmqgmevqphirlrkedvepvviivgdparteevanmcekkqelaynreyrsfrvvydsq
pitvishgigcpgtsiaieelaylgakviiragtcgslkpktlkqgdvcvtyaavnetgl
isnilpegfpcvatphvyqalmdaakelgieaasgigvtqdyfyqngilpsklemyskcc
dvidmemsgvlglcqargiatcgilavdgsplqwdegdydatgvkattgkenmvkitlka
canlrrqy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3mb8B (B:)
mplmqgmevqphirlrkedvepvviivgdparteevanmcekkqelaynreyrsfrvvyd
sqpitvishgigcpgtsiaieelaylgakviiragtcgslkpktlkqgdvcvtyaavnet
glisnilpegfpcvatphvyqalmdaakelgieaasgigvtqdyfyqngilpsklemysk
ccdvidmemsgvlglcqargiatcgilavdgsplqwdegdydatgvkattgkenmvkitl
kacanlrrqykgefeayveqkliseedlnsavdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3mb8B (B:)
lmqgmevqphirlrkedvepvviivgdparteevanmcekkqelaynreyrsfrvvydsq
pitvishgigcpgtsiaieelaylgakviiragtcgslkpktlkqgdvcvtyaavnetgl
isnilpegfpcvatphvyqalmdaakelgieaasgigvtqdyfyqngilpsklemyskcc
dvidmemsgvlglcqargiatcgilavdgsplqwdegdydatgvkattgkenmvkitlka
canlrrqy