PDB entry 3m5z

View 3m5z on RCSB PDB site
Description: Crystal structure of the mutant V182A,I218A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum
Class: lyase
Keywords: orotidine 5'-monophosphate decarboxylase, mutant V182A, I218A, LYASE
Deposited on 2010-03-14, released 2010-06-16
The last revision prior to the SCOPe 2.03 freeze date was dated 2010-06-16, with a file datestamp of 2010-06-11.
Experiment type: XRAY
Resolution: 1.35 Å
R-factor: 0.204
AEROSPACI score: 0.68 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: orotidine 5'-phosphate decarboxylase
    Species: Methanothermobacter thermautotrophicus str. Delta H [TaxId:187420]
    Gene: pyrF, MTH_129
    Database cross-references and differences (RAF-indexed):
    • Uniprot O26232
      • engineered (100)
      • engineered (217)
    Domains in SCOPe 2.03: d3m5za_
  • Chain 'B':
    Compound: orotidine 5'-phosphate decarboxylase
    Species: Methanothermobacter thermautotrophicus str. Delta H [TaxId:187420]
    Gene: pyrF, MTH_129
    Database cross-references and differences (RAF-indexed):
    • Uniprot O26232
      • engineered (100)
      • engineered (217)
    Domains in SCOPe 2.03: d3m5zb_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3m5zA (A:)
mrsrrvdvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefr
krfgcriiadfkvadipetnekicratfkagadaiivhgfpgadsvraclnvaeemgrev
flltemshpgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflisp
gagaqggdpgetlrfadaiivgrsiyladnpaaaaagaiesikdllnp

    Sequence, based on observed residues (ATOM records): (download) 
    >3m5zA (A:)
vdvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefrkrfgc
riiadfkvadipetnekicratfkagadaiivhgfpgadsvraclnvaeemgrevfllte
mshpgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflispggdpg
etlrfadaiivgrsiyladnpaaaaagaiesik

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3m5zB (B:)
mrsrrvdvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefr
krfgcriiadfkvadipetnekicratfkagadaiivhgfpgadsvraclnvaeemgrev
flltemshpgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflisp
gagaqggdpgetlrfadaiivgrsiyladnpaaaaagaiesikdllnp

    Sequence, based on observed residues (ATOM records): (download) 
    >3m5zB (B:)
vdvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefrkrfgc
riiadfkvadipetnekicratfkagadaiivhgfpgadsvraclnvaeemgrevfllte
mshpgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflispggdpg
etlrfadaiivgrsiyladnpaaaaagaiesik