PDB entry 3m4e

View 3m4e on RCSB PDB site
Description: Crystal structure of the M113N mutant of alpha-hemolysin bound to beta-cyclodextrin
Class: cell invasion
Keywords: beta barrel, cytolytic protein, Cytolysis, Hemolysis, Secreted, Toxin, CELL INVASION
Deposited on 2010-03-10, released 2010-05-05
The last revision prior to the SCOPe 2.04 freeze date was dated 2010-05-19, with a file datestamp of 2010-05-14.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.229
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha-hemolysin
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: hla, hly
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09616 (0-292)
      • engineered (112)
    Domains in SCOPe 2.04: d3m4ea_
  • Chain 'B':
    Compound: alpha-hemolysin
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: hla, hly
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09616 (0-292)
      • engineered (112)
    Domains in SCOPe 2.04: d3m4eb_
  • Chain 'C':
    Compound: alpha-hemolysin
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: hla, hly
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09616 (0-292)
      • engineered (112)
    Domains in SCOPe 2.04: d3m4ec_
  • Chain 'D':
    Compound: alpha-hemolysin
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: hla, hly
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09616 (0-292)
      • engineered (112)
    Domains in SCOPe 2.04: d3m4ed_
  • Chain 'E':
    Compound: alpha-hemolysin
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: hla, hly
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09616 (0-292)
      • engineered (112)
    Domains in SCOPe 2.04: d3m4ee_
  • Chain 'F':
    Compound: alpha-hemolysin
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: hla, hly
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09616 (0-292)
      • engineered (112)
    Domains in SCOPe 2.04: d3m4ef_
  • Chain 'G':
    Compound: alpha-hemolysin
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: hla, hly
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09616 (0-292)
      • engineered (112)
    Domains in SCOPe 2.04: d3m4eg_
  • Heterogens: BCD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3m4eA (A:)
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  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3m4eB (B:)
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iagqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeynstltygf
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pydrdswnpvygnqlfmktrngsmkaadnfldpnkassllssgfspdfatvitmdrkask
qqtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtn

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3m4eC (C:)
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ngnvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqnwg
pydrdswnpvygnqlfmktrngsmkaadnfldpnkassllssgfspdfatvitmdrkask
qqtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtn

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3m4eD (D:)
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iagqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeynstltygf
ngnvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqnwg
pydrdswnpvygnqlfmktrngsmkaadnfldpnkassllssgfspdfatvitmdrkask
qqtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtn

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3m4eE (E:)
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iagqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeynstltygf
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pydrdswnpvygnqlfmktrngsmkaadnfldpnkassllssgfspdfatvitmdrkask
qqtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtn

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3m4eF (F:)
adsdiniktgttdigsnttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkgt
iagqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeynstltygf
ngnvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqnwg
pydrdswnpvygnqlfmktrngsmkaadnfldpnkassllssgfspdfatvitmdrkask
qqtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtn

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3m4eG (G:)
adsdiniktgttdigsnttvktgdlvtydkengmhkkvfysfiddknhnkkllvirtkgt
iagqyrvyseeganksglawpsafkvqlqlpdnevaqisdyyprnsidtkeynstltygf
ngnvtgddtgkiggliganvsightlkyvqpdfktilesptdkkvgwkvifnnmvnqnwg
pydrdswnpvygnqlfmktrngsmkaadnfldpnkassllssgfspdfatvitmdrkask
qqtnidviyervrddyqlhwtstnwkgtntkdkwtdrsserykidwekeemtn