PDB entry 3m35
View 3m35 on RCSB PDB site
Description: Trypsin in complex with the inhibitor 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423)
Class: Hydrolase
Keywords: HYDROLASE, SERINE PROTEASE, DIGESTION, PANCREAS, ZYMOGEN, Disulfide bond, Metal-binding, Protease, Secreted
Deposited on
2010-03-08, released
2010-04-21
The last revision prior to the SCOPe 2.06 freeze date was dated
2010-04-21, with a file datestamp of
2010-04-16.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.221
AEROSPACI score: 0.38
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cationic trypsin
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3m35a_ - Heterogens: M35, CA, HOH