PDB entry 3m2x

View 3m2x on RCSB PDB site
Description: Carbonic Anhydrase II in complex with novel sulfonamide inhibitor
Class: lyase/lyase inhibitor
Keywords: 10 Stranded Twisted Beta-Sheets, Lyase, Disease mutation, Metal-binding, LYASE-LYASE INHIBITOR complex
Deposited on 2010-03-08, released 2011-05-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 1.87 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3m2xa_
  • Heterogens: ZN, BE7, BEX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3m2xA (A:)
gspefmshhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqat
slrilnnghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkya
aelhlvhwntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadf
tnfdprgllpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngege
peelmvdnwrpaqplknrqikasfk

    Sequence, based on observed residues (ATOM records): (download) 
    >3m2xA (A:)
hwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnng
hafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvhw
ntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdprgl
lpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelmvdn
wrpaqplknrqikasfk