PDB entry 3m17
View 3m17 on RCSB PDB site
Description: Crystal structure of human FcRn with a monomeric peptide inhibitor
Class: immune system/inhibitor
Keywords: IMMUNOGLOBULIN BINDING PROTEIN, Cell membrane, Disulfide bond, Glycoprotein, IgG-binding protein, Immunoglobulin domain, Membrane, Receptor, Transmembrane, Amyloid, Amyloidosis, Disease mutation, Glycation, Immune response, MHC I, Pyrrolidone carboxylic acid, Secreted, IMMUNE SYSTEM-INHIBITOR complex
Deposited on
2010-03-04, released
2010-06-16
The last revision prior to the SCOPe 2.02 freeze date was dated
2011-08-24, with a file datestamp of
2011-08-19.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.264
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: igg receptor fcrn large subunit p51
Species: Homo sapiens [TaxId:9606]
Gene: FCGRT, FCRN
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Gene: B2M, CDABP0092, HDCMA22P
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d3m17b_ - Chain 'C':
Compound: igg receptor fcrn large subunit p51
Species: Homo sapiens [TaxId:9606]
Gene: FCGRT, FCRN
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Gene: B2M, CDABP0092, HDCMA22P
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d3m17d_ - Chain 'E':
Compound: igg receptor fcrn large subunit p51
Species: Homo sapiens [TaxId:9606]
Gene: FCGRT, FCRN
Database cross-references and differences (RAF-indexed):
- Chain 'F':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Gene: B2M, CDABP0092, HDCMA22P
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d3m17f_ - Chain 'G':
Compound: igg receptor fcrn large subunit p51
Species: Homo sapiens [TaxId:9606]
Gene: FCGRT, FCRN
Database cross-references and differences (RAF-indexed):
- Chain 'H':
Compound: Beta-2-microglobulin
Species: Homo sapiens [TaxId:9606]
Gene: B2M, CDABP0092, HDCMA22P
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d3m17h_ - Chain 'I':
Compound: monomeric peptide inhibitor
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Chain 'J':
Compound: monomeric peptide inhibitor
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Chain 'K':
Compound: monomeric peptide inhibitor
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Chain 'L':
Compound: monomeric peptide inhibitor
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3m17B (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'C':
No sequence available.
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>3m17D (D:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'E':
No sequence available.
- Chain 'F':
Sequence; same for both SEQRES and ATOM records: (download)
>3m17F (F:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'G':
No sequence available.
- Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)
>3m17H (H:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'I':
No sequence available.
- Chain 'J':
No sequence available.
- Chain 'K':
No sequence available.
- Chain 'L':
No sequence available.