PDB entry 3m11
View 3m11 on RCSB PDB site
Description: Crystal Structure of Aurora A Kinase complexed with inhibitor
Class: transferase/transferase inhibitor
Keywords: Aurora kinase inhibitor, X-ray co-crystal analysis, Structure-based drug design, ATP-binding, Cell cycle, Cytoskeleton, Kinase, Nucleotide-binding, Phosphoprotein, Serine/threonine-protein kinase, Transferase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on
2010-03-03, released
2011-03-09
The last revision prior to the SCOPe 2.05 freeze date was dated
2011-03-09, with a file datestamp of
2011-03-04.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: 0.221
AEROSPACI score: 0.25
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: serine/threonine-protein kinase 6
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d3m11a_ - Heterogens: AKI, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3m11A (A:)
skkrqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrrev
eiqshlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelan
alsychskrvihrdikpenlllgsagelkiadfgwsvhapssrrtdlcgtldylppemie
grmhdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisr
llkhnpsqrpmlrevlehpwitansskpsncqnkesask
Sequence, based on observed residues (ATOM records): (download)
>3m11A (A:)
rqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiq
shlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanals
ychskrvihrdikpenlllgsagelkiadfgwsvhgtldylppemiegrmhdekvdlwsl
gvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqrpmlr
evlehpwitansskps