PDB entry 3luh

View 3luh on RCSB PDB site
Description: Crystal structure of MID domain from hAGO2 in complex with GMP
Class: RNA binding protein
Keywords: MID domain, Ribonucleoprotein, RNA-binding, RNA-mediated gene silencing, Translation regulation, RNA BINDING PROTEIN
Deposited on 2010-02-17, released 2010-05-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2010-06-30, with a file datestamp of 2010-06-25.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.188
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein argonaute-2
    Species: Homo sapiens [TaxId:9606]
    Gene: EIF2C2, AGO2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3luha_
  • Chain 'B':
    Compound: Protein argonaute-2
    Species: Homo sapiens [TaxId:9606]
    Gene: EIF2C2, AGO2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3luhb_
  • Chain 'C':
    Compound: Protein argonaute-2
    Species: Homo sapiens [TaxId:9606]
    Gene: EIF2C2, AGO2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3luhc_
  • Heterogens: 5GP, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3luhA (A:)
    snkqfhtgieikvwaiacfapqrqctevhlksfteqlrkisrdagmpiqgqpcfckyaqg
    adsvepmfrhlkntyaglqlvvvilpgktpvyaevkrvgdtvlgmatqcvqmknvqrttp
    qtlsnlclkinvklggvn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3luhA (A:)
    kqfhtgieikvwaiacfapqrqctevhlksfteqlrkisrdagmpiqgqpcfckyaqgad
    svepmfrhlkntyaglqlvvvilpgktpvyaevkrvgdtvlgmatqcvqmknvqrttpqt
    lsnlclkinvklg
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3luhB (B:)
    snkqfhtgieikvwaiacfapqrqctevhlksfteqlrkisrdagmpiqgqpcfckyaqg
    adsvepmfrhlkntyaglqlvvvilpgktpvyaevkrvgdtvlgmatqcvqmknvqrttp
    qtlsnlclkinvklggvn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3luhB (B:)
    kqfhtgieikvwaiacfapqrqctevhlksfteqlrkisrdagmpiqgqpcfckyaqgad
    svepmfrhlkntyaglqlvvvilpgktpvyaevkrvgdtvlgmatqcvqmknvqrttpqt
    lsnlclkinvklg
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3luhC (C:)
    snkqfhtgieikvwaiacfapqrqctevhlksfteqlrkisrdagmpiqgqpcfckyaqg
    adsvepmfrhlkntyaglqlvvvilpgktpvyaevkrvgdtvlgmatqcvqmknvqrttp
    qtlsnlclkinvklggvn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3luhC (C:)
    kqfhtgieikvwaiacfapqrqctevhlksfteqlrkisrdagmpiqgqpcfckyaqgad
    svepmfrhlkntyaglqlvvvilpgktpvyaevkrvgdtvlgmatqcvqmknvqrttpqt
    lsnlclkinvklg