PDB entry 3lt4

View 3lt4 on RCSB PDB site
Description: Enoyl-ACP Reductase from Plasmodium falciparum (PfENR) in complex with triclosan variant PB4
Class: oxidoreductase
Keywords: Triclosan, Triclosan variant, Enoyl-ACP reductase, oxidoreductase, P.falciparum
Deposited on 2010-02-15, released 2010-06-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-06-16, with a file datestamp of 2010-06-11.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.156
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Enoyl-ACP reductase
    Species: Plasmodium falciparum [TaxId:5833]
    Gene: FabI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3lt4a_
  • Chain 'B':
    Compound: Enoyl-ACP reductase
    Species: Plasmodium falciparum [TaxId:5833]
    Gene: FabI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3lt4b_
  • Heterogens: NAD, FB4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3lt4A (A:)
nedicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidk
dkkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhs
lanakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvp
gygggmssakaalesdtrvlayhlgrnynirintisagplksraatainklnntyenntn
qnknrnrhdvhnimnnsgekeekkisasqnytfidyaieysekyaplrqkllstdigsva
sfllsresraitgqtiyvdnglnimflpd

    Sequence, based on observed residues (ATOM records): (download) 
    >3lt4A (A:)
edicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidkd
kkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhsl
anakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvpg
ygggmssakaalesdtrvlayhlgrnynirintisagplksraataintfidyaieysek
yaplrqkllstdigsvasfllsresraitgqtiyvdnglnimflpd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3lt4B (B:)
nedicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidk
dkkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhs
lanakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvp
gygggmssakaalesdtrvlayhlgrnynirintisagplksraatainklnntyenntn
qnknrnrhdvhnimnnsgekeekkisasqnytfidyaieysekyaplrqkllstdigsva
sfllsresraitgqtiyvdnglnimflpd

    Sequence, based on observed residues (ATOM records): (download) 
    >3lt4B (B:)
nedicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidk
dkkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhs
lanakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvp
gygggmssakaalesdtrvlayhlgrnynirintisagplksraatainkltfidyaiey
sekyaplrqkllstdigsvasfllsresraitgqtiyvdnglnimflpd