PDB entry 3lrg

View 3lrg on RCSB PDB site
Description: Structure of anti-huntingtin VL domain
Class: immune system
Keywords: Huntington's disease, Huntingtin, Variable light chain domain, Intrabody, Immunoglobulin, IMMUNE SYSTEM
Deposited on 2010-02-11, released 2011-02-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-01-11, with a file datestamp of 2012-01-06.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.172
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: anti-huntingtin VL domain
    Species: Homo sapiens [TaxId:9606]
    Gene: VL12.3
    Database cross-references and differences (RAF-indexed):
    • PDB 3LRG
    Domains in SCOPe 2.07: d3lrga1, d3lrga2
  • Chain 'B':
    Compound: anti-huntingtin VL domain
    Species: Homo sapiens [TaxId:9606]
    Gene: VL12.3
    Database cross-references and differences (RAF-indexed):
    • PDB 3LRG
    Domains in SCOPe 2.07: d3lrgb1, d3lrgb2
  • Heterogens: TRS, IMD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3lrgA (A:)
mgsqpvltqspsvsaaprqrvtisvsgsnsnigsntvnwiqqlpgrapellmydddllap
gvsdrfsgsrsgtsasltisglqsedeadyyaatwddslngwvfgggtkvtvlsahhhhh
h

    Sequence, based on observed residues (ATOM records): (download) 
    >3lrgA (A:)
sqpvltqspsvsaaprqrvtisvsgsnsnigsntvnwiqqlpgrapellmydddllapgv
sdrfsgsrsgtsasltisglqsedeadyyaatwddslngwvfgggtkvtvlsah

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3lrgB (B:)
mgsqpvltqspsvsaaprqrvtisvsgsnsnigsntvnwiqqlpgrapellmydddllap
gvsdrfsgsrsgtsasltisglqsedeadyyaatwddslngwvfgggtkvtvlsahhhhh
h

    Sequence, based on observed residues (ATOM records): (download) 
    >3lrgB (B:)
vltqspsvsaaprqrvtisvsgsnsnigsntvnwiqqlpgrapellmydddllapgvsdr
fsgsrsgtsasltisglqsedeadyyaatwddslngwvfgggtkvtvls