PDB entry 3loj

View 3loj on RCSB PDB site
Description: Structure of Mycobacterium tuberculosis dUTPase H145A mutant
Class: hydrolase
Keywords: hydrolase, jelly roll, domain swapping, Nucleotide metabolism, Magnesium, Metal-binding
Deposited on 2010-02-04, released 2010-08-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.25 Å
R-factor: N/A
AEROSPACI score: 0.62 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: deoxyuridine 5'-triphosphate nucleotidohydrolase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: dut, MT2771, MTCY05A6.18c, Rv2697c
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A552 (20-173)
      • expression tag (12-15)
      • expression tag (18-19)
      • engineered mutation (164)
    Domains in SCOPe 2.08: d3loja1, d3loja2
  • Heterogens: DUP, GOL, TRS, MG, MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3lojA (A:)
mgsshhhhhhssglvprgshmsttlaivrldpglplpsrahdgdagvdlysaedvelapg
rralvrtgvavavpfgmvglvhprsglatrvglsivnspgtidagyrgeikvalinldpa
apivvhrgdriaqllvqrvelvelvevssfdeaglastsrgdggagssgghasl

    Sequence, based on observed residues (ATOM records): (download) 
    >3lojA (A:)
glvpshmsttlaivrldpglplpsrahdgdagvdlysaedvelapgrralvrtgvavavp
fgmvglvhprsglatrvglsivnspgtidagyrgeikvalinldpaapivvhrgdriaql
lvqrvelvelvevssfdeaglastsrgdggagssgghasl