PDB entry 3llr

View 3llr on RCSB PDB site
Description: Crystal structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 alpha
Class: transferase
Keywords: Transferase, DNA methyltransferase, methylysine binding, Structural Genomics Consortium, SGC, Alternative promoter usage, Chromatin regulator, DNA-binding, Metal-binding, Methyltransferase, Nucleus, Phosphoprotein, Repressor, S-adenosyl-L-methionine, Zinc-finger
Deposited on 2010-01-29, released 2010-03-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA (cytosine-5)-methyltransferase 3A
    Species: Homo sapiens [TaxId:9606]
    Gene: DNMT3A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3llra_
  • Chain 'B':
    Compound: DNA (cytosine-5)-methyltransferase 3A
    Species: Homo sapiens [TaxId:9606]
    Gene: DNMT3A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3llrb_
  • Chain 'C':
    Compound: DNA (cytosine-5)-methyltransferase 3A
    Species: Homo sapiens [TaxId:9606]
    Gene: DNMT3A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3llrc_
  • Chain 'D':
    Compound: DNA (cytosine-5)-methyltransferase 3A
    Species: Homo sapiens [TaxId:9606]
    Gene: DNMT3A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3llrd_
  • Chain 'E':
    Compound: DNA (cytosine-5)-methyltransferase 3A
    Species: Homo sapiens [TaxId:9606]
    Gene: DNMT3A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3llre_
  • Heterogens: BTB, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3llrA (A:)
gtkagddepeyedgrgfgigelvwgklrgfswwpgrivswwmtgrsraaegtrwvmwfgd
gkfsvvcveklmplssfcsafhqatynkqpmyrkaiyevlqvassragklfpvchdsdes
dtakavevqnkpmiewalggfqpsgpkgleppee

    Sequence, based on observed residues (ATOM records): (download) 
    >3llrA (A:)
eyedgrgfgigelvwgklrgfswwpgrivswwmtgrsraaegtrwvmwfgdgkfsvvcve
klmplssfcsafhqatynkqpmyrkaiyevlqvassragklfpavevqnkpmiewalggf
qpsgpkglepp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3llrB (B:)
gtkagddepeyedgrgfgigelvwgklrgfswwpgrivswwmtgrsraaegtrwvmwfgd
gkfsvvcveklmplssfcsafhqatynkqpmyrkaiyevlqvassragklfpvchdsdes
dtakavevqnkpmiewalggfqpsgpkgleppee

    Sequence, based on observed residues (ATOM records): (download) 
    >3llrB (B:)
peyedgrgfgigelvwgklrgfswwpgrivswwmtgrsraaegtrwvmwfgdgkfsvvcv
eklmplssfcsafhqatynkqpmyrkaiyevlqvassragklfpavevqnkpmiewalgg
fqpsgpkglepp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3llrC (C:)
gtkagddepeyedgrgfgigelvwgklrgfswwpgrivswwmtgrsraaegtrwvmwfgd
gkfsvvcveklmplssfcsafhqatynkqpmyrkaiyevlqvassragklfpvchdsdes
dtakavevqnkpmiewalggfqpsgpkgleppee

    Sequence, based on observed residues (ATOM records): (download) 
    >3llrC (C:)
eyedgrgfgigelvwgklrgfswwpgrivswwmtgrsraaegtrwvmwfgdgkfsvvcve
klmplssfcsafhqatynkqpmyrkaiyevlqvassragklfkavevqnkpmiewalggf
qpsgpkglepp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3llrD (D:)
gtkagddepeyedgrgfgigelvwgklrgfswwpgrivswwmtgrsraaegtrwvmwfgd
gkfsvvcveklmplssfcsafhqatynkqpmyrkaiyevlqvassragklfpvchdsdes
dtakavevqnkpmiewalggfqpsgpkgleppee

    Sequence, based on observed residues (ATOM records): (download) 
    >3llrD (D:)
eyedgrgfgigelvwgklrgfswwpgrivswwmtgrsraaegtrwvmwfgdgkfsvvcve
klmplssfcsafhqatynkqpmyrkaiyevlqvassragklfpvchdsdesdtakavevq
nkpmiewalggfqpsgpkglepp

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3llrE (E:)
gtkagddepeyedgrgfgigelvwgklrgfswwpgrivswwmtgrsraaegtrwvmwfgd
gkfsvvcveklmplssfcsafhqatynkqpmyrkaiyevlqvassragklfpvchdsdes
dtakavevqnkpmiewalggfqpsgpkgleppee

    Sequence, based on observed residues (ATOM records): (download) 
    >3llrE (E:)
eyedgrgfgigelvwgklrgfswwpgrivswwmtgrsraaegtrwvmwfgdgkfsvvcve
klmplssfcsafhqatynkqpmyrkaiyevlqvassragklfpakavevqnkpmiewalg
gfqpsgpkglepp