PDB entry 3liw

View 3liw on RCSB PDB site
Description: Factor XA in complex with (R)-2-(1-ADAMANTYLCARBAMOYLAMINO)-3-(3-CARBAMIDOYL-PHENYL)-N-PHENETHYL-PROPIONIC ACID AMIDE
Class: hydrolase
Keywords: COAGULATION FACTOR INHIBITOR, FACTOR XA, HYDROLASE, Blood coagulation, Calcium, Cleavage on pair of basic residues, Disulfide bond, EGF-like domain, Gamma-carboxyglutamic acid, Glycoprotein, Hydroxylation, Polymorphism, Protease, Secreted, Serine protease, Zymogen
Deposited on 2010-01-25, released 2010-04-07
The last revision prior to the SCOPe 2.06 freeze date was dated 2010-04-07, with a file datestamp of 2010-04-02.
Experiment type: XRAY
Resolution: 2.22 Å
R-factor: 0.223
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: activated factor xa heavy chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00742 (0-233)
  Domains in SCOPe 2.06: d3liwa_
• Chain 'B':
  Compound: factor x light chain
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00742 (0-50)
  Domains in SCOPe 2.06: d3liwb_
• Heterogens: CA, RUP, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3liwA (A:)
  ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
  qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
  tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
  cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3liwB (B:)
  lcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle