PDB entry 3liw

View 3liw on RCSB PDB site
Description: Factor XA in complex with (R)-2-(1-ADAMANTYLCARBAMOYLAMINO)-3-(3-CARBAMIDOYL-PHENYL)-N-PHENETHYL-PROPIONIC ACID AMIDE
Class: hydrolase
Keywords: COAGULATION FACTOR INHIBITOR, FACTOR XA, HYDROLASE, Blood coagulation, Calcium, Cleavage on pair of basic residues, Disulfide bond, EGF-like domain, Gamma-carboxyglutamic acid, Glycoprotein, Hydroxylation, Polymorphism, Protease, Secreted, Serine protease, Zymogen
Deposited on 2010-01-25, released 2010-04-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2010-04-07, with a file datestamp of 2010-04-02.
Experiment type: XRAY
Resolution: 2.22 Å
R-factor: 0.223
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: activated factor xa heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3liwa_
  • Chain 'B':
    Compound: factor x light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3liwb_
  • Heterogens: CA, RUP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3liwA (A:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3liwB (B:)
    lcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle