PDB entry 3li0

View 3li0 on RCSB PDB site
Description: Crystal structure of the mutant R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
Class: lyase
Keywords: mutant R203A, 6-hydroxyuridine-5'-phosphate, Decarboxylase, Pyrimidine biosynthesis, LYASE
Deposited on 2010-01-23, released 2010-06-16
The last revision prior to the SCOPe 2.02 freeze date was dated 2010-06-16, with a file datestamp of 2010-06-11.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.223
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: orotidine 5'-phosphate decarboxylase
    Species: METHANOTHERMOBACTER THERMAUTOTROPHICUS [TaxId:187420]
    Gene: pyrF, MTH_129
    Database cross-references and differences (RAF-indexed):
    • Uniprot O26232 (Start-227)
      • engineered (100)
      • engineered (202)
    Domains in SCOPe 2.02: d3li0a_
  • Chain 'B':
    Compound: orotidine 5'-phosphate decarboxylase
    Species: METHANOTHERMOBACTER THERMAUTOTROPHICUS [TaxId:187420]
    Gene: pyrF, MTH_129
    Database cross-references and differences (RAF-indexed):
    • Uniprot O26232
      • engineered (100)
      • engineered (202)
    Domains in SCOPe 2.02: d3li0b_
  • Heterogens: BMQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3li0A (A:)
    mrsrrvdvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefr
    krfgcriiadfkvadipetnekicratfkagadaiivhgfpgadsvraclnvaeemgrev
    flltemshpgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflisp
    gvgaqggdpgetlrfadaiivgasiyladnpaaaaagiiesikdllnp
    

    Sequence, based on observed residues (ATOM records): (download)
    >3li0A (A:)
    srrvdvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefrkr
    fgcriiadfkvadipetnekicratfkagadaiivhgfpgadsvraclnvaeemgrevfl
    ltemshpgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflispgv
    gaqggdpgetlrfadaiivgasiyladnpaaaaagiiesikdllnp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3li0B (B:)
    mrsrrvdvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefr
    krfgcriiadfkvadipetnekicratfkagadaiivhgfpgadsvraclnvaeemgrev
    flltemshpgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflisp
    gvgaqggdpgetlrfadaiivgasiyladnpaaaaagiiesikdllnp
    

    Sequence, based on observed residues (ATOM records): (download)
    >3li0B (B:)
    srrvdvmdvmnrlilamdlmnrddalrvtgevreyidtvkigyplvlsegmdiiaefrkr
    fgcriiadfkvadipetnekicratfkagadaiivhgfpgadsvraclnvaeemgrevfl
    ltemshpgaemfiqgaadeiarmgvdlgvknyvgpstrperlsrlreiigqdsflispgv
    gaqggdpgetlrfadaiivgasiyladnpaaaaagiiesikdll