PDB entry 3ldn

View 3ldn on RCSB PDB site
Description: Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in apo form
Class: chaperone
Keywords: GRP78, HSP70, HSC70, CHAPERONE, HEAT SHOCK, PROTEIN FOLDING, ATP-BINDING, ADENOSINE, NUCLEOSIDE, NUCLEOTIDE-BINDING, STRESS RESPONSE, SMALL MOLECULE INHIBITOR, SELECTIVITY, Endoplasmic reticulum, Phosphoprotein
Deposited on 2010-01-13, released 2011-01-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-06-29, with a file datestamp of 2011-06-24.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.2
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 78 kDa glucose-regulated protein
    Species: Homo sapiens [TaxId:9606]
    Gene: HSPA5, GRP78
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ldna1, d3ldna2
  • Chain 'B':
    Compound: 78 kDa glucose-regulated protein
    Species: Homo sapiens [TaxId:9606]
    Gene: HSPA5, GRP78
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ldnb1, d3ldnb2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ldnA (A:)
gsdvgtvvgidlgttyscvgvfkngrveiiandqgnritpsyvaftpegerligdaaknq
ltsnpentvfdakrligrtwndpsvqqdikflpfkvvekktkpyiqvdigggqtktfape
eisamvltkmketaeaylgkkvthavvtvpayfndaqrqatkdagtiaglnvmriinept
aaaiaygldkregeknilvfdlgggtfdvslltidngvfevvatngdthlggedfdqrvm
ehfiklykkktgkdvrkdnravqklrrevekakralssqhqarieiesfyegedfsetlt
rakfeelnmdlfrstmkpvqkvledsdlkksdideivlvggstripkiqqlvkeffngke
psrginpdeavaygaavqagvlsg

    Sequence, based on observed residues (ATOM records): (download) 
    >3ldnA (A:)
dvgtvvgidlgttyscvgvfkngrveiiandqgnritpsyvaftpegerligdaaknqlt
snpentvfdakrligrtwndpsvqqdikflpfkvvekktkpyiqvdigggqtktfapeei
samvltkmketaeaylgkkvthavvtvpayfndaqrqatkdagtiaglnvmriineptaa
aiaygldkregeknilvfdlgggtfdvslltidngvfevvatngdthlggedfdqrvmeh
fiklykkktgkdvrkdnravqklrrevekakralssqhqarieiesfyegedfsetltra
kfeelnmdlfrstmkpvqkvledsdlkksdideivlvggstripkiqqlvkeffngkeps
rginpdeavaygaavqagvlsg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3ldnB (B:)
gsdvgtvvgidlgttyscvgvfkngrveiiandqgnritpsyvaftpegerligdaaknq
ltsnpentvfdakrligrtwndpsvqqdikflpfkvvekktkpyiqvdigggqtktfape
eisamvltkmketaeaylgkkvthavvtvpayfndaqrqatkdagtiaglnvmriinept
aaaiaygldkregeknilvfdlgggtfdvslltidngvfevvatngdthlggedfdqrvm
ehfiklykkktgkdvrkdnravqklrrevekakralssqhqarieiesfyegedfsetlt
rakfeelnmdlfrstmkpvqkvledsdlkksdideivlvggstripkiqqlvkeffngke
psrginpdeavaygaavqagvlsg

    Sequence, based on observed residues (ATOM records): (download) 
    >3ldnB (B:)
dvgtvvgidlgttyscvgvfkngrveiiandqgnritpsyvaftpegerligdaaknqlt
snpentvfdakrligrtwndpsvqqdikflpfkvvekktkpyiqvdigggqtktfapeei
samvltkmketaeaylgkkvthavvtvpayfndaqrqatkdagtiaglnvmriineptaa
aiaygldkregeknilvfdlgggtfdvslltidngvfevvatngdthlggedfdqrvmeh
fiklykkktgkdvrkdnravqklrrevekakralssqhqarieiesfyegedfsetltra
kfeelnmdlfrstmkpvqkvledsdlkksdideivlvggstripkiqqlvkeffngkeps
rginpdeavaygaavqagvlsg