PDB entry 3l9p

View 3l9p on RCSB PDB site
Description: Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain
Class: transferase
Keywords: kinase domain, ATP-binding, Glycoprotein, Kinase, Membrane, Nucleotide-binding, Phosphoprotein, Proto-oncogene, Receptor, Transferase, Transmembrane, Tyrosine-protein kinase
Deposited on 2010-01-05, released 2010-07-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-09-08, with a file datestamp of 2010-09-03.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.192
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Anaplastic lymphoma kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: ALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UM73
      • engineered (237)
    Domains in SCOPe 2.08: d3l9pa_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3l9pA (A:)
msyyhhhhhhdydipttenlyfqgamgselqspeyklsklrtstimtdynpnycfagkts
sisdlkevprknitlirglghgafgevyegqvsgmpndpsplqvavktlpevcseqdeld
flmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretrprpsqpsslam
ldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfgmardiyragyy
rkggcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympypsksnqevlefvt
sggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvintalpieygp
lveeeek

    Sequence, based on observed residues (ATOM records): (download) 
    >3l9pA (A:)
npnycfagktssisdlkevprknitlirglghgafgevyegqvsgsplqvavktlpevcs
eqdeldflmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretrprpsq
psslamldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfgmardi
yragyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympypsksnqe
vlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvintal
pie