PDB entry 3l5x

View 3l5x on RCSB PDB site
Description: Crystal structure of the complex between IL-13 and H2L6 FAB
Class: immune system
Keywords: immunoglobulin fold, alpha-helical bundle, Cytokine, Disulfide bond, Glycoprotein, Polymorphism, Secreted, MONOCLONAL ANTIBODY, IMMUNE SYSTEM
Deposited on 2009-12-22, released 2010-04-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-25, with a file datestamp of 2019-12-20.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-13
    Species: Homo sapiens [TaxId:9606]
    Gene: IL13, NC30
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3l5xa_
  • Chain 'H':
    Compound: h2l6 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3L5X (0-223)
    Domains in SCOPe 2.08: d3l5xh_
  • Chain 'L':
    Compound: h2l6 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3L5X (0-213)
    Domains in SCOPe 2.08: d3l5xl1, d3l5xl2
  • Heterogens: MES, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3l5xA (A:)
mgpvppstalrelieelvnitqnqkaplcngsmvwsinltagmycaaleslinvsgcsai
ektqrmlsgfcphkvsagqfsslhvrdtkievaqfvkdlllhlkklfregrfn

    Sequence, based on observed residues (ATOM records): (download) 
    >3l5xA (A:)
stalrelieelvnitqplcngsmvwsinltagmycaaleslinvsgcsaiektqrmlsgf
cphkvsagqfsslhvrdtkievaqfvkdlllhlkklfregr

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3l5xH (H:)
evtlkesgpvlvkptetltltctvsgfslstygmgvgwirqppgkalewlahiwwddvkr
ynpalksrltiskdtsksqvvltmtnmdpvdtatyycarmgsdydvwfdywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3l5xL (L:)
eivltqspatlslspgeratlscrasksiskylawyqqkpgqaprlliysgstlqsgipa
rfsgsgsgtdftltisslepedfavyycqqhneypytfgqgtkleikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec