PDB entry 3l5u
View 3l5u on RCSB PDB site
Description: Crystal structure of macrophage migration inhibitory factor (MIF) with benzothiazole inhibitor at 1.90A resolution
Class: isomerase
Keywords: PROTEIN-LIGAND COMPLEX, CYTOKINE, CYTOPLASM, IMMUNE RESPONSE, INFLAMMATORY RESPONSE, INNATE IMMUNITY, ISOMERASE, PHOSPHOPROTEIN, SECRETED, Acetylation
Deposited on
2009-12-22, released
2010-03-09
The last revision prior to the SCOPe 2.07 freeze date was dated
2017-11-01, with a file datestamp of
2017-10-27.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: macrophage migration inhibitory factor
Species: Homo sapiens [TaxId:9606]
Gene: GLIF, MIF, MMIF
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d3l5ua1, d3l5ua2 - Chain 'B':
Compound: macrophage migration inhibitory factor
Species: Homo sapiens [TaxId:9606]
Gene: GLIF, MIF, MMIF
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d3l5ub1, d3l5ub2 - Chain 'C':
Compound: macrophage migration inhibitory factor
Species: Homo sapiens [TaxId:9606]
Gene: GLIF, MIF, MMIF
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d3l5uc_ - Heterogens: ZEC, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3l5uA (A:)
pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfalehhhh
hh
Sequence, based on observed residues (ATOM records): (download)
>3l5uA (A:)
pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfale
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3l5uB (B:)
pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfalehhhh
hh
Sequence, based on observed residues (ATOM records): (download)
>3l5uB (B:)
pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfal
- Chain 'C':
Sequence, based on SEQRES records: (download)
>3l5uC (C:)
pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfalehhhh
hh
Sequence, based on observed residues (ATOM records): (download)
>3l5uC (C:)
pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa