PDB entry 3l2q

View 3l2q on RCSB PDB site
Description: Crystal structure of the Prototype Foamy Virus (PFV) intasome in apo form
Class: recombination/DNA
Keywords: PROTEIN-DNA COMPLEX, TETRAMER, DNA INTEGRATION, ENDONUCLEASE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, DNA-BINDING, ZINC BINDING, HHCC MOTIF, VIRAL PROTEIN, RECOMBINATION, RECOMBINATION-DNA complex
Deposited on 2009-12-15, released 2010-02-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-03-16, with a file datestamp of 2010-03-12.
Experiment type: XRAY
Resolution: 3.25 Å
R-factor: 0.198
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: integrase
    Species: Human spumaretrovirus [TaxId:11963]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14350
      • variant (219-220)
    Domains in SCOPe 2.08: d3l2qa1, d3l2qa2, d3l2qa3
  • Chain 'B':
    Compound: integrase
    Species: Human spumaretrovirus [TaxId:11963]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14350
      • variant (219-220)
  • Chain 'C':
    Compound: 5'-d(*ap*tp*tp*gp*tp*cp*ap*tp*gp*gp*ap*ap*tp*tp*tp*tp*gp*tp*a)-3'
  • Chain 'D':
    Compound: 5'-d(*tp*ap*cp*ap*ap*ap*ap*tp*tp*cp*cp*ap*tp*gp*ap*cp*a)-3'
  • Heterogens: ZN, GOL

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3l2qA (A:)
gpgcntkkpnldaeldqllqghyikgypkqytyfledgkvkvsrpegvkiippqsdrqki
vlqahnlahtgreatllkianlywwpnmrkdvvkqlgrcqqclitnasnkasgpilrpdr
pqkpfdkffidyigplppsqgylyvlvvvdgmtgftwlyptkapstsatvkslnvltsia
ipkvihsdqgaaftsstfaewakergihlefstpyhpqssgkverknsdikrlltkllvg
rptkwydllpvvqlalnntyspvlkytphqllfgidsntpfanqdtldltreeelsllqe
irtslyhpstppassrswspvvgqlvqervarpaslrprwhkpstvlkvlnprtvvildh
lgnnrtvsidnlkptshqngttndtatmdhlekne

    Sequence, based on observed residues (ATOM records): (download) 
    >3l2qA (A:)
aeldqllqghyikgypkqytyfledgkvkvsrpegvkiippqsdrqkivlqahnlahtgr
eatllkianlywwpnmrkdvvkqlgrcqqclitnasnkasgpilrpdrpqkpfdkffidy
igplppsqgylyvlvvvdgmtgftwlyptkapstsatvkslnvltsiaipkvihsdqgaa
ftsstfaewakergihlefstpyhpqssgkverknsdikrlltkllvgrptkwydllpvv
qlalnntyspvlkytphqllfgidsntpfanqdtldltreeelsllqeirtslyhpstpp
assrswspvvgqlvqervarpaslrprwhkpstvlkvlnprtvvildhlgnnrtvsidnl
kptsh

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.