PDB entry 3kwy

View 3kwy on RCSB PDB site
Description: Crystal structure of RXRalpha ligand binding domain in complex with triphenyltin and a coactivator fragment
Class: transcription
Keywords: nuclear receptor transcription organotin, DNA-binding, Host-virus interaction, Isopeptide bond, Metal-binding, Nucleus, Receptor, Transcription, Transcription regulation, Zinc-finger, Activator, Phosphoprotein
Deposited on 2009-12-02, released 2010-01-19
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.186
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Retinoic acid receptor RXR-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: RXRA, NR2B1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3kwya_
  • Chain 'B':
    Compound: Nuclear receptor coactivator 2 peptide
    Database cross-references and differences (RAF-indexed):
  • Heterogens: T9T, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3kwyA (A:)
gshmtssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlft
lvewakriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsah
sagvgaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvya
sleayckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleap
hqmt

    Sequence, based on observed residues (ATOM records): (download) 
    >3kwyA (A:)
dmpverileaelavepdpvtnicqaadkqlftlvewakriphfselplddqvillragwn
elliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdkte
lgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalr
siglkclehlfffkligdidtflmemleap

  • Chain 'B':
    No sequence available.