PDB entry 3kt2

View 3kt2 on RCSB PDB site
Description: Crystal Structure of N88D mutant HIV-1 Protease
Class: hydrolase
Keywords: Drug Resistant Mutation, N88D, Nelfinavir, HIV-1 protease, Hydrolase, Protease
Deposited on 2009-11-24, released 2010-02-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-08-23, with a file datestamp of 2017-08-18.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protease
    Species: Human immunodeficiency virus type 1 [TaxId:11706]
    Gene: gag-pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04585 (104-202)
      • engineered (87)
      • engineered (94)
      • engineered (191)
      • engineered (198)
    Domains in SCOPe 2.07: d3kt2a1, d3kt2a2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3kt2A (A:)
pqvtlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrdlltqigmtlnfggssgpqvtlwqrplvtikig
gqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqydqilieicghkaigtvl
vgptpvniigrdlltqigmtlnf

    Sequence, based on observed residues (ATOM records): (download) 
    >3kt2A (A:)
pqvtlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrdlltqigmtlnfpqvtlwqrplvtikiggqlke
alldtgaddtvleemslpgrwkpkmiggiggfikvrqydqilieicghkaigtvlvgptp
vniigrdlltqigmtlnf