PDB entry 3ks9

View 3ks9 on RCSB PDB site
Description: Metabotropic glutamate receptor mGluR1 complexed with LY341495 antagonist
Class: signaling protein
Keywords: Glutamate Receptors, mGluR1, Dimerization, Glutamic Acid Binding, Structural Genomics, Structural Genomics Consortium, SGC, Cell membrane, G-protein coupled receptor, Glycoprotein, Membrane, Phosphoprotein, Receptor, Transducer, Transmembrane, SIGNALING PROTEIN
Deposited on 2009-11-20, released 2009-12-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Metabotropic glutamate receptor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: GPRC1A, GRM1, MGLUR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13255
      • engineered (226)
    Domains in SCOPe 2.08: d3ks9a_
  • Chain 'B':
    Compound: Metabotropic glutamate receptor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: GPRC1A, GRM1, MGLUR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13255
      • engineered (226)
    Domains in SCOPe 2.08: d3ks9b_
  • Heterogens: Z99, MG, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ks9A (A:)
llagassqrsvarmdgdviigalfsvhhqppaekvperkcgeireqygiqrveamfhtld
kinadpvllpnitlgseirdscwhssvaleqsiefirdslisirdekdginrclpdgqsl
ppgrtkkpiagvigpgsssvaiqvqnllqlfdipqiaysatsidlsdktlykyflrvvps
dtlqaramldivkrynwtyvsavhtegnygesgmdafkelaaqeglsiahsdkiysnage
ksfdrllrklrerlpkarvvvcfcegmtvrgllsamrrlgvvgefsligsdgwadrdevi
egyeveanggitiklqspevrsfddyflklrldtntrnpwfpefwqhrfqcrlpghllen
pnfkrictgnesleenyvqdskmgfvinaiyamahglqnmhhalcpghvglcdamkpidg
sklldflikssfigvsgeevwfdekgdapgrydimnlqyteanrydyvhvgtwhegvlni
ddykiqmnksglvprg

    Sequence, based on observed residues (ATOM records): (download) 
    >3ks9A (A:)
qrsvarmdgdviigalfsvhhqppaekvperkcgeireqygiqrveamfhtldkinadpv
llpnitlgseirdscwhssvaleqsiefirdslkpiagvigpgsssvaiqvqnllqlfdi
pqiaysatsidlsdktlykyflrvvpsdtlqaramldivkrynwtyvsavhtegnygesg
mdafkelaaqeglsiahsdkiysnageksfdrllrklrerlpkarvvvcfcegmtvrgll
samrrlgvvgefsligsdgwadrdeviegyeveanggitiklqspevrsfddyflklrld
tntrnpwfpefwqhrfqcrlpgpnfkrictgnesleenyvqdskmgfvinaiyamahglq
nmhhalcpghvglcdamkpidgsklldflikssfigvsgeevwfdekgdapgrydimnlq
yterydyvhvgtwhegvlniddyki

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3ks9B (B:)
llagassqrsvarmdgdviigalfsvhhqppaekvperkcgeireqygiqrveamfhtld
kinadpvllpnitlgseirdscwhssvaleqsiefirdslisirdekdginrclpdgqsl
ppgrtkkpiagvigpgsssvaiqvqnllqlfdipqiaysatsidlsdktlykyflrvvps
dtlqaramldivkrynwtyvsavhtegnygesgmdafkelaaqeglsiahsdkiysnage
ksfdrllrklrerlpkarvvvcfcegmtvrgllsamrrlgvvgefsligsdgwadrdevi
egyeveanggitiklqspevrsfddyflklrldtntrnpwfpefwqhrfqcrlpghllen
pnfkrictgnesleenyvqdskmgfvinaiyamahglqnmhhalcpghvglcdamkpidg
sklldflikssfigvsgeevwfdekgdapgrydimnlqyteanrydyvhvgtwhegvlni
ddykiqmnksglvprg

    Sequence, based on observed residues (ATOM records): (download) 
    >3ks9B (B:)
qrsvarmdgdviigalfsvhhqppaekvperkcgeireqygiqrveamfhtldkinadpv
llpnitlgseirdscwhssvaleqsiefirdslkpiagvigpgsssvaiqvqnllqlfdi
pqiaysatsidlsdktlykyflrvvpsdtlqaramldivkrynwtyvsavhtegnygesg
mdafkelaaqeglsiahsdkiysnageksfdrllrklrerlpkarvvvcfcegmtvrgll
samrrlgvvgefsligsdgwadrdeviegyeveanggitiklqspevrsfddyflklrld
tntrnpwfpefwqhrfqcrlpnfkrictgnesleenyvqdskmgfvinaiyamahglqnm
hhalcpghvglcdamkpidgsklldflikssfigvsgeevwfdekgdapgrydimnlqyt
eanrydyvhvgtwhegvlnidd