PDB entry 3krb

View 3krb on RCSB PDB site
Description: Structure of Aldose Reductase from Giardia Lamblia at 1.75A Resolution
Class: oxidoreductase
Keywords: SSGCID, SBRI, EMERALD BIOSTRUCTURES, UNIVERSITY OF WASHINGTON, NIH, NIAID, ALDOSE REDUCTASE, GIARDIA LAMBLIA, Oxidoreductase, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease
Deposited on 2009-11-18, released 2009-12-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-09-21, with a file datestamp of 2011-09-16.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.145
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aldose reductase
    Species: Giardia lamblia [TaxId:184922]
    Gene: GL50803_7260
    Database cross-references and differences (RAF-indexed):
    • Uniprot A8BGX6 (21-333)
      • expression tag (20)
    Domains in SCOPe 2.08: d3krba1, d3krba2
  • Chain 'B':
    Compound: aldose reductase
    Species: Giardia lamblia [TaxId:184922]
    Gene: GL50803_7260
    Database cross-references and differences (RAF-indexed):
    • Uniprot A8BGX6 (21-333)
      • expression tag (20)
    Domains in SCOPe 2.08: d3krbb1, d3krbb2
  • Heterogens: NAP, UNX, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3krbA (A:)
mahhhhhhmgtleaqtqgpgsmqypprlgfgtwqappeavqtavetalmtgyrhidcayv
yqneeaigrafgkifkdassgikredvwitsklwnynhrpelvreqckktmsdlqvdyld
lflvhwplafvrndvgdlfpkdaegramlekvpladtwrameqlveeglvkhigvsnytv
plladllnyakikplvnqieihpwhpndatvkfcldngigvtayspmggsyadprdpsgt
qknvilecktlkaiadakgtsphcvalawhvkkwntsmysvipksqtparieanfkctev
qlsdddmdainnihlnkrirfcdpaifwkvplfd

    Sequence, based on observed residues (ATOM records): (download) 
    >3krbA (A:)
smqypprlgfgtwqappeavqtavetalmtgyrhidcayvyqneeaigrafgkifkdass
gikredvwitsklwnynhrpelvreqckktmsdlqvdyldlflvhwplafvrndvgdlfp
kdaegramlekvpladtwrameqlveeglvkhigvsnytvplladllnyakikplvnqie
ihpwhpndatvkfcldngigvtayspmggsyatqknvilecktlkaiadakgtsphcval
awhvkkwntsmysvipksqtparieanfkctevqlsdddmdainnihlnkrirfcdpaif
wkvplfd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3krbB (B:)
mahhhhhhmgtleaqtqgpgsmqypprlgfgtwqappeavqtavetalmtgyrhidcayv
yqneeaigrafgkifkdassgikredvwitsklwnynhrpelvreqckktmsdlqvdyld
lflvhwplafvrndvgdlfpkdaegramlekvpladtwrameqlveeglvkhigvsnytv
plladllnyakikplvnqieihpwhpndatvkfcldngigvtayspmggsyadprdpsgt
qknvilecktlkaiadakgtsphcvalawhvkkwntsmysvipksqtparieanfkctev
qlsdddmdainnihlnkrirfcdpaifwkvplfd

    Sequence, based on observed residues (ATOM records): (download) 
    >3krbB (B:)
smqypprlgfgtwqappeavqtavetalmtgyrhidcayvyqneeaigrafgkifkdass
gikredvwitsklwnynhrpelvreqckktmsdlqvdyldlflvhwplafvrndvgdlfp
kdaegramlekvpladtwrameqlveeglvkhigvsnytvplladllnyakikplvnqie
ihpwhpndatvkfcldngigvtayspmggsyatqknvilecktlkaiadakgtsphcval
awhvkkwntsmysvipksqtparieanfkctevqlsdddmdainnihlnkrirfcdpaif
wkvplfd