PDB entry 3kpp

View 3kpp on RCSB PDB site
Description: Crystal Structure of HLA B*4405 in complex with EEYLQAFTY a self peptide from the ABCD3 protein
Class: immune system
Keywords: HLA B*4405, allorecognition, TCR recognition, self peptide, Disulfide bond, Glycoprotein, Host-virus interaction, Immune response, Membrane, MHC I, Transmembrane, IMMUNE SYSTEM
Deposited on 2009-11-16, released 2009-12-22
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.188
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, B-44 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-B, HLAB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30481 (0-275)
      • variant (115)
    Domains in SCOPe 2.06: d3kppa1, d3kppa2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3kppb_
  • Chain 'C':
    Compound: EEYLQAFTY, self peptide from the ATP binding cassette protein ABCD3
    Database cross-references and differences (RAF-indexed):
    • PDB 3KPP (0-8)
  • Heterogens: PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3kppA (A:)
    gshsmryfytamsrpgrgeprfitvgyvddtlfvrfdsdatsprkeprapwieqegpeyw
    dretqisktntqtyrenlrtalryynqseagshiiqrmygcdvgpdgrllrgydqyaydg
    kdyialnedlsswtaadtaaqitqrkweaarvaeqdrayleglcveslrrylengketlq
    radppkthvthhpisdhevtlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
    fqkwaavvvpsgeeqrytchvqheglpkpltlrwep
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >3kppB (B:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.