PDB entry 3kou

View 3kou on RCSB PDB site
Description: Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally flexible covalent enzyme-substrate complex.
Class: Hydrolase
Keywords: CD38, CYCLIC ADP RIBOSE, ECTO-ADP-RIBOSYL CYCLASE, 2 GLYCOSIDASE, HYDROLASE, Glycosidase
Deposited on 2009-11-13, released 2010-10-27
The last revision prior to the SCOPe 2.01 freeze date was dated 2010-10-27, with a file datestamp of 2010-10-22.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: 0.203
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: CD38 molecule
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3koua_
  • Chain 'B':
    Compound: CD38 molecule
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3koub_
  • Heterogens: SO4, 2NF, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3kouA (A:)
ykwhysglnrwhgagstadfqkiiqercdtytqtirpgsrsrncqairqafmsafiskdp
ckatkedynslinlapptvpcgqqvfwsktkelaheyakrrrlmtledtllgyladglrw
cgepgssdlniwscpdwrkdcrtnylsvfwevlserfaesacntvrvvlngslenafdsm
sifgrveapnlrpqveleawlvhdtgkppsdscsgssirklksildgrnvkfrcmdnlsr
dqflqrs

    Sequence, based on observed residues (ATOM records): (download) 
    >3kouA (A:)
rwhgagstadfqkiiqercdtytqtirpgsrsrncqairqafmsafiskdpckatkedyn
slinlapptvpcgqqvfwsktkelaheyakrrrlmtledtllgyladglrwcgepgssdl
niwscpdwrkdcrtnylsvfwevlserfaesacntvrvvlngslenafdsmsifgrveap
nlrpqveleawlvhdtgkppsdscsgssirklksildgrnvkfrcmdnlsrdqflqr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3kouB (B:)
ykwhysglnrwhgagstadfqkiiqercdtytqtirpgsrsrncqairqafmsafiskdp
ckatkedynslinlapptvpcgqqvfwsktkelaheyakrrrlmtledtllgyladglrw
cgepgssdlniwscpdwrkdcrtnylsvfwevlserfaesacntvrvvlngslenafdsm
sifgrveapnlrpqveleawlvhdtgkppsdscsgssirklksildgrnvkfrcmdnlsr
dqflqrs

    Sequence, based on observed residues (ATOM records): (download) 
    >3kouB (B:)
lnrwhgagstadfqkiiqercdtytqtirpgsrsrncqairqafmsafiskdpckatked
ynslinlapptvpcgqqvfwsktkelaheyakrrrlmtledtllgyladglrwcgepgss
dlniwscpdwrkdcrtnylsvfwevlserfaesacntvrvvlngslenafdsmsifgrve
apnlrpqveleawlvhdtgkppsdscsgssirklksildgrnvkfrcmdnlsrdqflq