PDB entry 3kmm

View 3kmm on RCSB PDB site
Description: Structure of human LCK kinase with a small molecule inhibitor
Class: transferase/transferase inhibitor
Keywords: TYROSINE KINASE, ATP-binding, Kinase, Nucleotide-binding, Phosphoprotein, Transferase, Tyrosine-protein kinase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2009-11-10, released 2010-12-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-03-07, with a file datestamp of 2018-03-02.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proto-oncogene tyrosine-protein kinase LCK
    Species: Homo sapiens [TaxId:9606]
    Gene: LCK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3kmma_
  • Heterogens: LHL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3kmmA (A:)
mhhhhhhpqkpwwedewevpretlklverlgagqfgevwmgyynghtkvavkslkqgsms
pdaflaeanlmkqlqhqrlvrlyavvtqepiyiiteymengslvdflktpsgikltinkl
ldmaaqiaegmafieernyihrdlraanilvsdtlsckiadfglarliedneytaregak
fpikwtapeainygtftiksdvwsfgillteivthgripypgmtnpeviqnlergyrmvr
pdncpeelyqlmrlcwkerpedrptfdylrsvledfftategqfqpqp

    Sequence, based on observed residues (ATOM records): (download) 
    >3kmmA (A:)
kpwwedewevpretlklverlgagqfgevwmgyynghtkvavkslkqgsmspdaflaean
lmkqlqhqrlvrlyavvtqepiyiiteymengslvdflktpsgikltinklldmaaqiae
gmafieernyihrdlraanilvsdtlsckiadfglarliedneytaregakfpikwtape
ainygtftiksdvwsfgillteivthgripypgmtnpeviqnlergyrmvrpdncpeely
qlmrlcwkerpedrptfdylrsvledfftat