PDB entry 3kj1

View 3kj1 on RCSB PDB site
Description: Mcl-1 in complex with Bim BH3 mutant I2dA
Class: apoptosis
Keywords: bcl-2, bh3, apoptosis, protein-peptide complex, Alternative splicing, Cytoplasm, Developmental protein, Differentiation, Isopeptide bond, Membrane, Mitochondrion, Nucleus, Phosphoprotein, Polymorphism, Transmembrane, Ubl conjugation
Deposited on 2009-11-02, released 2010-02-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
  Species: Homo sapiens [TaxId:9606]
  Gene: BCL2L3, mcl-1, MCL1
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q07820 (2-End)
    • expression tag (1)
  Domains in SCOPe 2.08: d3kj1a1, d3kj1a2
• Chain 'B':
  Compound: Bcl-2-like protein 11
  Species: Homo sapiens [TaxId:9606]
  Gene: BCL2L11, BIM
  Database cross-references and differences (RAF-indexed):
  • Uniprot O43521 (0-20)
    • engineered (5)
    • expression tag (21)
• Heterogens: ZN, ACT, CL, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >3kj1A (A:)
  gsdelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafq
  gmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciep
  laesitdvlvrtkrdwlvkqrgwdgfveffhvedlegg
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >3kj1A (A:)
  sdelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafqg
  mlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepl
  aesitdvlvrtkrdwlvkqrgwdgfveffhve
  

  
  
• Chain 'B':
  No sequence available.