PDB entry 3kgt
View 3kgt on RCSB PDB site
Description: V30M mutant human transthyretin (TTR) complexed with genistein (V30M:GEN) pH 7.5
Class: transport protein
Keywords: TRANSPORT PROTEIN, TTR, TRANSTHYRETIN, AMYLOID, Amyloidosis, Cytoplasm, Disease mutation, Hormone, Neuropathy, Polymorphism, Secreted, Thyroid hormone, Transport
Deposited on
2009-10-29, released
2010-03-23
The last revision prior to the SCOPe 2.06 freeze date was dated
2010-05-19, with a file datestamp of
2010-05-14.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.199
AEROSPACI score: 0.45
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: PALB, TTR
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3kgta_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: PALB, TTR
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3kgtb_ - Heterogens: GEN, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3kgtA (A:)
gptgtgeskcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>3kgtA (A:)
cplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3kgtB (B:)
gptgtgeskcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>3kgtB (B:)
cplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftanrrytiaallspysysttavvtnp