PDB entry 3kex

View 3kex on RCSB PDB site
Description: Crystal structure of the catalytically inactive kinase domain of the human epidermal growth factor receptor 3 (HER3)
Class: transferase
Keywords: kinase domain, inactive kinase, HER3, ErbB3, ATP-binding, Cell membrane, Kinase, Membrane, Nucleotide-binding, Phosphoprotein, Receptor, Transferase, Tyrosine-protein kinase
Deposited on 2009-10-26, released 2009-12-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Receptor tyrosine-protein kinase erbB-3
    Species: Homo sapiens [TaxId:9606]
    Gene: ERBB3, ErbB3/HER3, HER3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3kexa_
  • Chain 'B':
    Compound: Receptor tyrosine-protein kinase erbB-3
    Species: Homo sapiens [TaxId:9606]
    Gene: ERBB3, ErbB3/HER3, HER3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3kexb_
  • Heterogens: ANP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3kexA (A:)
gamkvlarifketelrklkvlgsgvfgtvhkgvwipegesikipvcikviedksgrqsfq
avtdhmlaigsldhahivrllglcpgsslqlvtqylplgslldhvrqhrgalgpqlllnw
gvqiakgmyyleehgmvhrnlaarnvllkspsqvqvadfgvadllppddkqllyseaktp
ikwmalesihfgkythqsdvwsygvtvwelmtfgaepyaglrlaevpdllekgerlaqpq
ictidvymvmvkcwmidenirptfkelaneftrmardpprylvikresgpgiapgpephg
ltnkkleevelepeldldldleaee

    Sequence, based on observed residues (ATOM records): (download) 
    >3kexA (A:)
kvlarifketelrklkvlgsgvfgtvhkgvwipegesikipvcikviedksgrqsfqavt
dhmlaigsldhahivrllglcpgsslqlvtqylplgslldhvrqhrgalgpqlllnwgvq
iakgmyyleehgmvhrnlaarnvllkspsqvqvadfgvadllppddkqlltpikwmales
ihfgkythqsdvwsygvtvwelmtfgaepyaglrlaevpdllekgerlaqpqictidvym
vmvkcwmidenirptfkelaneftrmardpprylvikresgpgiapgpephg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3kexB (B:)
gamkvlarifketelrklkvlgsgvfgtvhkgvwipegesikipvcikviedksgrqsfq
avtdhmlaigsldhahivrllglcpgsslqlvtqylplgslldhvrqhrgalgpqlllnw
gvqiakgmyyleehgmvhrnlaarnvllkspsqvqvadfgvadllppddkqllyseaktp
ikwmalesihfgkythqsdvwsygvtvwelmtfgaepyaglrlaevpdllekgerlaqpq
ictidvymvmvkcwmidenirptfkelaneftrmardpprylvikresgpgiapgpephg
ltnkkleevelepeldldldleaee

    Sequence, based on observed residues (ATOM records): (download) 
    >3kexB (B:)
kvlarifketelrklkvlgsgvfgtvhkgvwipegesikipvcikviedksgrqsfqavt
dhmlaigsldhahivrllglcpgsslqlvtqylplgslldhvrqhrgalgpqlllnwgvq
iakgmyyleehgmvhrnlaarnvllkspsqvqvadfgvadllppddkqtpikwmalesih
fgkythqsdvwsygvtvwelmtfgaepyaglrlaevpdllekgerlaqpqictidvymvm
vkcwmidenirptfkelaneftrmardpprylvikregpgiap