PDB entry 3kdt

View 3kdt on RCSB PDB site
Description: Crystal structure of peroxisome proliferator-activatedeceptor alpha (PPARalpha) complex with N-3-((2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl)methoxy)benzyl)-N-(methoxycarbonyl)glycine
Class: hormone receptor
Keywords: Nuclear Hormone Receptor, transcription regulation, Activator, DNA-binding, Lipid-binding, Receptor, Transcription, HORMONE RECEPTOR
Deposited on 2009-10-23, released 2010-04-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2010-04-28, with a file datestamp of 2010-04-23.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.256
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisome proliferator-activated receptor alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: PPARA, NR1C1, PPAR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3kdta_
  • Chain 'B':
    Compound: Peroxisome proliferator-activated receptor alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: PPARA, NR1C1, PPAR
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07869 (4-276)
      • expression tag (1-3)
    Domains in SCOPe 2.08: d3kdtb1, d3kdtb2
  • Heterogens: 7HA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3kdtA (A:)
gshmedsetadlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmae
ktlvaklvangiqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllky
gvyeaifamlssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnaleld
dsdislfvaaiiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkma
dlrqlvtehaqlvqiikktesdaalhpllqeiyrdmy

    Sequence, based on observed residues (ATOM records): (download) 
    >3kdtA (A:)
setadlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmaektlvai
qnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvyeaifamlss
vmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdislfvaaii
ccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrqlvtehaql
vqiikktesdaalhpllqeiyrdmy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3kdtB (B:)
gshmedsetadlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmae
ktlvaklvangiqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllky
gvyeaifamlssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnaleld
dsdislfvaaiiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkma
dlrqlvtehaqlvqiikktesdaalhpllqeiyrdmy

    Sequence, based on observed residues (ATOM records): (download) 
    >3kdtB (B:)
shmedsetadlkslakriyeaylknfnmnkvkarvilsgkannppfvihdmetlcmaekt
lvvangiqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvyea
ifamlssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdis
lfvaaiiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrql
vtehaqlvqiikktesdaalhpllqeiyrdmy