PDB entry 3k7w

View 3k7w on RCSB PDB site
Description: Protein phosphatase 2A core complex bound to dinophysistoxin-2
Class: signaling protein/hydrolase
Keywords: PROTEIN-PROTEIN COMPLEX, HEAT REPEAT, SIGNALING PROTEIN, PHOSPHATASE, LIGAND SPECIFICITY, Acetylation, Polymorphism, Centromere, Cytoplasm, Cytoskeleton, Hydrolase, Iron, Manganese, Metal-binding, Methylation, Nucleus, Phosphoprotein, Protein phosphatase
Deposited on 2009-10-13, released 2009-11-03
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-12-01, with a file datestamp of 2009-11-27.
Experiment type: XRAY
Resolution: 2.96 Å
R-factor: 0.222
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP2R1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3k7wa_
  • Chain 'C':
    Compound: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP2CA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3k7wc_
  • Heterogens: SO4, XT2, MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3k7wA (A:)
maaadgddslypiavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiy
dedevllalaeqlgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehs
psdleahfvplvkrlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpm
vrraaasklgefakvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedl
ealvmptlrqaaedkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevra
aashkvkefcenlsadcrenvimsqilpcikelvsdanqhvksalasvimglspilgkdn
tiehllplflaqlkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvr
laiieympllagqlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewaha
tiipkvlamsgdpnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnv
akslqkigpildnstlqsevkpilekltqdqdvdvkyfaqealtvlsla

    Sequence, based on observed residues (ATOM records): (download) 
    >3k7wA (A:)
slypiavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiydedevlla
laeqlgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehspsdleahf
vplvkrlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpmvrraaask
lgefakvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedlealvmptl
rqaaedkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevraaashkvke
fcenlsadcrenvimsqilpcikelvsdanqhvksalasvimglspilgkdntiehllpl
flaqlkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvrlaiieymp
llagqlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewahatiipkvla
msgdpnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnvakslqkig
pildnstlqsevkpilekltqdqdvdvkyfaqealtvlsla

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3k7wC (C:)
mdekvftkeldqwieqlneckqlsesqvkslcekakeiltkesnvqevrcpvtvcgdvhg
qfhdlmelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvryreritilrgnhes
rqitqvygfydeclrkygnanvwkyftdlfdylpltalvdgqifclhgglspsidtldhi
raldrlqevphegpmcdllwsdpddrggwgisprgagytfgqdisetfnhangltlvsra
hqlvmegynwchdrnvvtifsapnycyrcgnqaaimelddtlkysflqfdpaprrgephv
trrtpdyfl

    Sequence, based on observed residues (ATOM records): (download) 
    >3k7wC (C:)
ftkeldqwieqlneckqlsesqvkslcekakeiltkesnvqevrcpvtvcgdvhgqfhdl
melfriggkspdtnylfmgdyvdrgyysvetvtllvalkvryreritilrgnhesrqitq
vygfydeclrkygnanvwkyftdlfdylpltalvdgqifclhgglspsidtldhiraldr
lqevphegpmcdllwsdpddrggwgisprgagytfgqdisetfnhangltlvsrahqlvm
egynwchdrnvvtifsapnycyrcgnqaaimelddtlkysflqfdpap