PDB entry 3k7v

View 3k7v on RCSB PDB site
Description: Protein phosphatase 2A core complex bound to dinophysistoxin-1
Class: signaling protein/hydrolase
Keywords: PROTEIN-PROTEIN COMPLEX, HEAT REPEAT, SIGNALING PROTEIN, PHOSPHATASE, LIGAND SPECIFICITY, Acetylation, Polymorphism, Centromere, Cytoplasm, Cytoskeleton, Hydrolase, Iron, Manganese, Metal-binding, Methylation, Nucleus, Phosphoprotein, Protein phosphatase
Deposited on 2009-10-13, released 2009-11-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-12-01, with a file datestamp of 2009-11-27.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: 0.217
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP2R1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3k7va_
  • Chain 'C':
    Compound: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP2CA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3k7vc_
  • Heterogens: SO4, XT1, MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3k7vA (A:)
    maaadgddslypiavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiy
    dedevllalaeqlgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehs
    psdleahfvplvkrlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpm
    vrraaasklgefakvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedl
    ealvmptlrqaaedkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevra
    aashkvkefcenlsadcrenvimsqilpcikelvsdanqhvksalasvimglspilgkdn
    tiehllplflaqlkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvr
    laiieympllagqlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewaha
    tiipkvlamsgdpnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnv
    akslqkigpildnstlqsevkpilekltqdqdvdvkyfaqealtvlsla
    

    Sequence, based on observed residues (ATOM records): (download)
    >3k7vA (A:)
    slypiavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiydedevlla
    laeqlgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehspsdleahf
    vplvkrlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpmvrraaask
    lgefakvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedlealvmptl
    rqaaedkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevraaashkvke
    fcenlsadcrenvimsqilpcikelvsdanqhvksalasvimglspilgkdntiehllpl
    flaqlkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvrlaiieymp
    llagqlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewahatiipkvla
    msgdpnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnvakslqkig
    pildnstlqsevkpilekltqdqdvdvkyfaqealtvlsla
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3k7vC (C:)
    mdekvftkeldqwieqlneckqlsesqvkslcekakeiltkesnvqevrcpvtvcgdvhg
    qfhdlmelfriggkspdtnylfmgdyvdrgyysvetvtllvalkvryreritilrgnhes
    rqitqvygfydeclrkygnanvwkyftdlfdylpltalvdgqifclhgglspsidtldhi
    raldrlqevphegpmcdllwsdpddrggwgisprgagytfgqdisetfnhangltlvsra
    hqlvmegynwchdrnvvtifsapnycyrcgnqaaimelddtlkysflqfdpaprrgephv
    trrtpdyfl
    

    Sequence, based on observed residues (ATOM records): (download)
    >3k7vC (C:)
    ftkeldqwieqlneckqlsesqvkslcekakeiltkesnvqevrcpvtvcgdvhgqfhdl
    melfriggkspdtnylfmgdyvdrgyysvetvtllvalkvryreritilrgnhesrqitq
    vygfydeclrkygnanvwkyftdlfdylpltalvdgqifclhgglspsidtldhiraldr
    lqevphegpmcdllwsdpddrggwgisprgagytfgqdisetfnhangltlvsrahqlvm
    egynwchdrnvvtifsapnycyrcgnqaaimelddtlkysflqfdpap