PDB entry 3k2u
View 3k2u on RCSB PDB site
Description: Crystal structure of HGFA in complex with the allosteric inhibitory antibody Fab40
Class: hydrolase/immune system
Keywords: Serine Protease, Allosteric inhibitor, Antibody, EGF-like domain, GLYCOPROTEIN, Fab complex, HYDROLASE, Disulfide bond, Kringle, Protease, Secreted, Zymogen, HYDROLASE-IMMUNE SYSTEM complex
Deposited on
2009-09-30, released
2009-12-15
The last revision prior to the SCOPe 2.05 freeze date was dated
2012-03-28, with a file datestamp of
2012-03-23.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.239
AEROSPACI score: 0.3
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Hepatocyte growth factor activator long chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: Hepatocyte growth factor activator short chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'H':
Compound: Antibody, Fab fragment, Heavy Chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'L':
Compound: Antibody, Fab fragment, Light Chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d3k2ul1, d3k2ul2 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
No sequence available.
- Chain 'H':
No sequence available.
- Chain 'L':
Sequence, based on SEQRES records: (download)
>3k2uL (L:)
diqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliysasflysgvps
rfsgsgsgtdftltisslqpedfatyycqqsnrapatfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec
Sequence, based on observed residues (ATOM records): (download)
>3k2uL (L:)
diqmtqspsslsasvgdrvtitcrasqdvstavawyqqkpgkapklliysasflysgvps
rfsgsgsgtdftltisslqpedfatyycqqsnrapatfgqgtkveikrtvaapsvfifpp
sdeqltasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdstyslsstltlskady
ekhkvyacevthqglsspvtksfnrgec