PDB entry 3jzk

View 3jzk on RCSB PDB site
Description: crystal structure of MDM2 with chromenotriazolopyrimidine 1
Class: ligase
Keywords: MDM2, p53, inhibitor, Alternative splicing, Cytoplasm, Host-virus interaction, Ligase, Metal-binding, Nucleus, Phosphoprotein, Proto-oncogene, Ubl conjugation, Ubl conjugation pathway, Zinc, Zinc-finger
Deposited on 2009-09-23, released 2009-11-17
The last revision prior to the SCOPe 2.01 freeze date was dated 2010-04-28, with a file datestamp of 2010-04-23.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.3
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: E3 ubiquitin-protein ligase Mdm2
  Species: Homo sapiens [TaxId:9606]
  Gene: MDM2
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q00987
  Domains in SCOPe 2.01: d3jzka_
• Heterogens: YIN, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >3jzkA (A:)
  gsqipaseqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhiv
  ycsndllgdlfgvpsfsvkehrkiytmiyrnlvvvn
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >3jzkA (A:)
  qipaseqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhivyc
  sndllgdlfgvpsfsvkehrkiytmiyrnlvvv