PDB entry 3jy9

View 3jy9 on RCSB PDB site
Description: Janus Kinase 2 Inhibitors
Class: transferase
Keywords: kinase, inhibitor, jak2, janus kinase, ATP-binding, Disease mutation, Membrane, Nucleotide-binding, Phosphoprotein, Proto-oncogene, SH2 domain, Transferase, Tyrosine-protein kinase
Deposited on 2009-09-21, released 2009-12-01
The last revision prior to the SCOPe 2.03 freeze date was dated 2013-04-03, with a file datestamp of 2013-03-29.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.201
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase JAK2
    Species: Homo sapiens [TaxId:9606]
    Gene: JAK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3jy9a_
  • Heterogens: JZH, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3jy9A (A:)
mgsshhhhhhssglvprgshnmtqfeerhlkflqqlgkgnfgsvemcrydplqdntgevv
avkklqhsteehlrdfereieilkslqhdnivkykgvcysagrrnlklimeylpygslrd
ylqkhkeridhikllqytsqickgmeylgtkryihrdlatrnilvenenrvkigdfgltk
vlpqdkeyykvkepgespifwyapeslteskfsvasdvwsfgvvlyelftyieksksppa
efmrmigndkqgqmivfhliellknngrlprpdgcpdeiymimtecwnnnvnqrpsfrdl
alrvdqirdnm

    Sequence, based on observed residues (ATOM records): (download) 
    >3jy9A (A:)
tqfeerhlkflqqlgkggsvemcrydplqdntgevvavkklqhsteehlrdfereieilk
slqhdnivkykgvcysrnlklimeylpygslrdylqkhkeridhikllqytsqickgmey
lgtkryihrdlatrnilvenenrvkigdfgltkvlpqdkeyykvkepgespifwyapesl
teskfsvasdvwsfgvvlyelftyieksksppaefmrmigndkqgqmivfhliellknng
rlprpdgcpdeiymimtecwnnnvnqrpsfrdlalrvdqirdnm