PDB entry 3js3

View 3js3 on RCSB PDB site
Description: Crystal structure of type I 3-dehydroquinate dehydratase (aroD) from Clostridium difficile with covalent reaction intermediate
Class: lyase
Keywords: Type I 3-Dehydroquinate Dehydratase, aroD, covalent reaction intermediate, Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Lyase, Schiff base, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID
Deposited on 2009-09-09, released 2009-09-22
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.192
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-dehydroquinate dehydratase
    Species: Clostridium difficile [TaxId:272563]
    Gene: aroD, CD2217
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3js3a_
  • Chain 'B':
    Compound: 3-dehydroquinate dehydratase
    Species: Clostridium difficile [TaxId:272563]
    Gene: aroD, CD2217
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3js3b_
  • Chain 'C':
    Compound: 3-dehydroquinate dehydratase
    Species: Clostridium difficile [TaxId:272563]
    Gene: aroD, CD2217
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3js3c_
  • Chain 'D':
    Compound: 3-dehydroquinate dehydratase
    Species: Clostridium difficile [TaxId:272563]
    Gene: aroD, CD2217
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3js3d_
  • Heterogens: DHS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3js3A (A:)
snamkrkvqvknitigegrpkicvpiigknkkdiikeakelkdacldiiewrvdffenve
nikevkevlyelrsyihdipllftfrsvveggeklisrdyyttlnkeisntglvdlidve
lfmgdevidevvnfahkkevkviisnhdfnktpkkeeivsrlcrmqelgadlpkiavmpq
nekdvlvlleatnemfkiyadrpiitmsmsgmgvisrlcgeifgsaltfgaaksvsapgq
isfkelnsvlnllhksin

    Sequence, based on observed residues (ATOM records): (download) 
    >3js3A (A:)
mkrkvqvknitigegrpkicvpiigknkkdiikeakelkdacldiiewrvdffenvenik
evkevlyelrsyihdipllftfrsvveggeklisrdyyttlnkeisntglvdlidvelfm
gdevidevvnfahkkevkviisnhdfnktpkkeeivsrlcrmqelgadlpkiavmpqnek
dvlvlleatnemfkiyadrpiitmsmsgmgvisrlcgeifgsaltfgaaksvsapgqisf
kelnsvlnllhks

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3js3B (B:)
snamkrkvqvknitigegrpkicvpiigknkkdiikeakelkdacldiiewrvdffenve
nikevkevlyelrsyihdipllftfrsvveggeklisrdyyttlnkeisntglvdlidve
lfmgdevidevvnfahkkevkviisnhdfnktpkkeeivsrlcrmqelgadlpkiavmpq
nekdvlvlleatnemfkiyadrpiitmsmsgmgvisrlcgeifgsaltfgaaksvsapgq
isfkelnsvlnllhksin

    Sequence, based on observed residues (ATOM records): (download) 
    >3js3B (B:)
mkrkvqvknitigegrpkicvpiigknkkdiikeakelkdacldiiewrvdffenvenik
evkevlyelrsyihdipllftfrsvveggeklisrdyyttlnkeisntglvdlidvelfm
gdevidevvnfahkkevkviisnhdfnktpkkeeivsrlcrmqelgadlpkiavmpqnek
dvlvlleatnemfkiyadrpiitmsmsgmgvisrlcgeifgsaltfgaaksvsapgqisf
kelnsvlnllhks

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3js3C (C:)
snamkrkvqvknitigegrpkicvpiigknkkdiikeakelkdacldiiewrvdffenve
nikevkevlyelrsyihdipllftfrsvveggeklisrdyyttlnkeisntglvdlidve
lfmgdevidevvnfahkkevkviisnhdfnktpkkeeivsrlcrmqelgadlpkiavmpq
nekdvlvlleatnemfkiyadrpiitmsmsgmgvisrlcgeifgsaltfgaaksvsapgq
isfkelnsvlnllhksin

    Sequence, based on observed residues (ATOM records): (download) 
    >3js3C (C:)
mkrkvqvknitigegrpkicvpiigknkkdiikeakelkdacldiiewrvdffenvenik
evkevlyelrsyihdipllftfrsvveggeklisrdyyttlnkeisntglvdlidvelfm
gdevidevvnfahkkevkviisnhdfnktpkkeeivsrlcrmqelgadlpkiavmpqnek
dvlvlleatnemfkiyadrpiitmsmsgmgvisrlcgeifgsaltfgaaksvsapgqisf
kelnsvlnllhks

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3js3D (D:)
snamkrkvqvknitigegrpkicvpiigknkkdiikeakelkdacldiiewrvdffenve
nikevkevlyelrsyihdipllftfrsvveggeklisrdyyttlnkeisntglvdlidve
lfmgdevidevvnfahkkevkviisnhdfnktpkkeeivsrlcrmqelgadlpkiavmpq
nekdvlvlleatnemfkiyadrpiitmsmsgmgvisrlcgeifgsaltfgaaksvsapgq
isfkelnsvlnllhksin

    Sequence, based on observed residues (ATOM records): (download) 
    >3js3D (D:)
mkrkvqvknitigegrpkicvpiigknkkdiikeakelkdacldiiewrvdffenvenik
evkevlyelrsyihdipllftfrsvveggeklisrdyyttlnkeisntglvdlidvelfm
gdevidevvnfahkkevkviisnhdfnktpkkeeivsrlcrmqelgadlpkiavmpqnek
dvlvlleatnemfkiyadrpiitmsmsgmgvisrlcgeifgsaltfgaaksvsapgqisf
kelnsvlnllhks