PDB entry 3ix6

View 3ix6 on RCSB PDB site
Description: Crystal structure of Thymidylate synthase thyA from Brucella melitensis
Class: transferase
Keywords: NIAID, SSGCID, Seattle Structural Center for Infectious Disease, brucellosis, orchitis, epididymitis, mastitis, thymidylate, Methyltransferase, Nucleotide biosynthesis, Transferase, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease
Deposited on 2009-09-03, released 2009-09-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.215
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Brucella melitensis [TaxId:29459]
    Gene: thyA, BMEI0608
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Thymidylate synthase
    Species: Brucella melitensis [TaxId:29459]
    Gene: thyA, BMEI0608
    Database cross-references and differences (RAF-indexed):
    • Uniprot P67042 (96-End)
      • expression tag (91-95)
    Domains in SCOPe 2.08: d3ix6b1, d3ix6b2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3ix6B (B:)
mghhhhhhsgevkpevkpethinlkvsdgsseiffkikkttplrrlmeafakrqgkemds
lrflydgiriqadqtpedldmedndiieahreqiggmrtyldllqhvldhgvdrddrtgt
gtrsvfgyqmrfdleegfpvlttkklhlrsiihellwflkgdtniaylkengvtiwdewa
dengdlgpvygyqwrswpapdgrhidqianllkmlhtnpqsrrlivsawnpalvdemalp
pchclfqfyvangrlscqlyqrsadiflgvpfniasyalltmmiaqvtglkpgefihtlg
dahiysnhfeqarlqltrtpkklpvmhinpdvkdlfafrfedfrldgyeadptikapiav

    Sequence, based on observed residues (ATOM records): (download) 
    >3ix6B (B:)
eqiggmrtyldllqhvldhgvdrgtrsvfgyqmrfdleegfpvlttkhlrsiihellwfl
kgdtniaylkengvtiwdewadengdlgpvygyqwrswpapdgrhidqianllkmlhtnp
qsrrlivsawnpalvdemalppchclfqfyvangrlscqlyqrsadiflgvpfniasyal
ltmmiaqvtglkpgefihtlgdahiysnhfeqarlqltrtpkklpvmhinpdvkdlfafr
fedfrldg