PDB entry 3iwe

View 3iwe on RCSB PDB site
Description: Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD85646
Class: transferase
Keywords: Transferase, N-myristoyltransferase, NMT, Acyltransferase, Phosphoprotein, Structural Genomics, Structural Genomics Consortium, SGC
Deposited on 2009-09-02, released 2009-09-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 1.79 Å
R-factor: 0.182
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycylpeptide N-tetradecanoyltransferase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NMT, NMT1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3iwea1, d3iwea2
  • Chain 'B':
    Compound: Glycylpeptide N-tetradecanoyltransferase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NMT, NMT1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3iweb1, d3iweb2
  • Heterogens: MYA, 646, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3iweA (A:)
grsyqfwdtqpvpklgevvnthgpvepdkdnirqepytlpqgftwdaldlgdrgvlkely
tllnenyvedddnmfrfdyspefllwalrppgwlpqwhcgvrvvssrklvgfisaipani
hiydtekkmveinflcvhkklrskrvapvlireitrrvhlegifqavytagvvlpkpvgt
crywhrslnprklievkfshlsrnmtmqrtmklyrlpetpktaglrpmetkdipvvhqll
trylkqfhltpvmsqeevehwfypqeniidtfvvenangevtdflsfytlpstimnhpth
kslkaaysfynvhtqtplldlmsdalvlakmkgfdvfnaldlmenktfleklkfgigdgn
lqyylynwkcpsmgaekvglvlq

    Sequence, based on observed residues (ATOM records): (download) 
    >3iweA (A:)
rsyqfwdtqpvpklgevvnthgpvepdkdnirqepytlpqgftwdaldlgdrgvlkelyt
llnenyvedddnmfrfdyspefllwalrppgwlpqwhcgvrvvssrklvgfisaipanih
iydtekkmveinflcvhkklrskrvapvlireitrrvhlegifqavytagvvlpkpvgtc
rywhrslnprklievkfshlsrnmtmqrtmklyrlpetpktaglrpmetkdipvvhqllt
rylkqfhltpvmsqeevehwfypqeniidtfvvenangevtdflsfytlpstimnhpthk
slkaaysfynvhtqtplldlmsdalvlakmkgfdvfnaldlmenktfleklkfgigdgnl
qyylynwkcpsmgaekvglvlq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3iweB (B:)
grsyqfwdtqpvpklgevvnthgpvepdkdnirqepytlpqgftwdaldlgdrgvlkely
tllnenyvedddnmfrfdyspefllwalrppgwlpqwhcgvrvvssrklvgfisaipani
hiydtekkmveinflcvhkklrskrvapvlireitrrvhlegifqavytagvvlpkpvgt
crywhrslnprklievkfshlsrnmtmqrtmklyrlpetpktaglrpmetkdipvvhqll
trylkqfhltpvmsqeevehwfypqeniidtfvvenangevtdflsfytlpstimnhpth
kslkaaysfynvhtqtplldlmsdalvlakmkgfdvfnaldlmenktfleklkfgigdgn
lqyylynwkcpsmgaekvglvlq

    Sequence, based on observed residues (ATOM records): (download) 
    >3iweB (B:)
syqfwdtqpvpklgevvnthgpvepdkdnirqepytlpqgftwdaldlgdrgvlkelytl
lnenyvedddnmfrfdyspefllwalrppgwlpqwhcgvrvvssrklvgfisaipanihi
ydtekkmveinflcvhkklrskrvapvlireitrrvhlegifqavytagvvlpkpvgtcr
ywhrslnprklievkfshlsrnmtmqrtmklyrlpetpktaglrpmetkdipvvhqlltr
ylkqfhltpvmsqeevehwfypqeniidtfvvenangevtdflsfytlpstimnhpthks
lkaaysfynvhtqtplldlmsdalvlakmkgfdvfnaldlmenktfleklkfgigdgnlq
yylynwkcpsmgaekvglvlq