PDB entry 3iw2

View 3iw2 on RCSB PDB site
Description: Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125 in complex with econazole
Class: oxidoreductase
Keywords: econazole, cytochrome P450, tuberculosis, monooxygenase, cholesterol, Heme, Iron, Metal-binding, Oxidoreductase
Deposited on 2009-09-02, released 2009-11-03
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.19 Å
R-factor: 0.165
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 CYP125
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: cyp125, MT3649, MTCY03C7.11, Rv3545c
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3iw2a_
  • Heterogens: EKO, HEM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3iw2A (A:)
mswnhqsveiavrrttvpspnlppgfdftdpaiyaerlpvaefaelrsaapiwwngqdpg
kgggfhdggfwaitklndvkeisrhsdvfssyengviprfkndiaredievqrfvmlnmd
aphhtrlrkiisrgftpravgrlhdelqeraqkiaaeaaaagsgdfveqvscelplqaia
gllgvpqedrgklfhwsnemtgnedpeyahidpkassaeligyamkmaeekaknpaddiv
tqliqadidgeklsddefgffvvmlavagnettrnsitqgmmafaehpdqwelykkvrpe
taadeivrwatpvtafqrtalrdyelsgvqikkgqrvvmfyrsanfdeevfqdpftfnil
rnpnphvgfggtgahyciganlarmtinlifnavadhmpdlkpisaperlrsgwlngikh
wqvdytgrcpvah

    Sequence, based on observed residues (ATOM records): (download) 
    >3iw2A (A:)
pnlppgfdftdpaiyaerlpvaefaelrsaapiwwngqdpgkgggfhdggfwaitklndv
keisrhsdvfssyengviprfkndiaredievqrfvmlnmdaphhtrlrkiisrgftpra
vgrlhdelqeraqkiaaeaaaagsgdfveqvscelplqaiagllgvpqedrgklfhwsne
mtgnedpeyahidpkassaeligyamkmaeekivtqliqadgeklsddefgffvvmlava
gnettrnsitqgmmafaehpdqwelykkvrpetaadeivrwatpvtafqrtalrdyelsg
vqikkgqrvvmfyrsanfdeevfqdpftfnilrnpnphvgfggtgahyciganlarmtin
lifnavadhmpdlkpisaperlrsgwlngikhwqvdyt