PDB entry 3itd

View 3itd on RCSB PDB site
Description: Crystal structure of an inactive 17beta-Hydroxysteroid dehydrogenase (Y167F mutated form) from fungus Cochliobolus lunatus
Class: oxidoreductase
Keywords: Hydroxysteroid dehydrogenase, Short Chain Dehydrogenase/reductase, SDR, steroid, Fungi, Cochliobolus lunatus, OXIDOREDUCTASE
Deposited on 2009-08-28, released 2010-08-18
The last revision prior to the SCOPe 2.05 freeze date was dated 2010-08-18, with a file datestamp of 2010-08-13.
Experiment type: XRAY
Resolution: 1.89 Å
R-factor: 0.169
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 17beta-hydroxysteroid dehydrogenase
    Species: Cochliobolus lunatus [TaxId:5503]
    Gene: 17HSDcl
    Database cross-references and differences (RAF-indexed):
    • Uniprot O93874 (Start-269)
      • engineered (166)
    Domains in SCOPe 2.05: d3itda_
  • Heterogens: GOL, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3itdA (A:)
mphvenasetyipgrldgkvalvtgsgrgigaavavhlgrlgakvvvnyanstkdaekvv
seikalgsdaiaikadirqvpeivklfdqavahfghldiavsnsgvvsfghlkdvteeef
drvfslntrgqffvareayrhlteggrivltssntskdfsvpkhslfsgskgavdsfvri
fskdcgdkkitvnavapggtvtdmfhevshhyipngtsytaeqrqqmaahasplhrngwp
qdvanvvgflvskegewvngkvltldggaa

    Sequence, based on observed residues (ATOM records): (download) 
    >3itdA (A:)
yipgrldgkvalvtgsgrgigaavavhlgrlgakvvvnyanstkdaekvvseikalgsda
iaikadirqvpeivklfdqavahfghldiavsnsgvvsfghlkdvteeefdrvfslntrg
qffvareayrhlteggrivltssntskdfsvpkhslfsgskgavdsfvrifskdcgdkki
tvnavapggtvtdmfhevshhyipngtsytaeqrqqmaahasplhrngwpqdvanvvgfl
vskegewvngkvltldggaa